The effect of lactation on the mineral distribution profile of the rat femur by single photon absorptiometry.

The effect of lactation on the mineral distribution profile of the rat femur by single photon absorptiometry.
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通过单光子吸收法观察哺乳对大鼠股骨矿物质分布剖面的影响。

DOI:
10.1016/8756-3282(85)90319-9
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发表时间:
1985
期刊:
影响因子:
4.1
通讯作者:
Myers,RC
Myers,RC
中科院分区:
医学2区
文献类型:
--
作者:
Hagaman,JR;Sanchez,TV;Myers,RC

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使用单光子吸收法对哺乳期和非哺乳期对照大鼠切除的股骨中骨矿物质的分布进行定位和定量。沿股骨长度以九个连续的 0.32 cm 增量在近远端测量骨矿物质含量,然后绘制为距股骨近端距离的函数。这些图描述了矿物质分布情况,并揭示了哺乳后的骨质流失是特定部位的,干骺端区域(23-36%)比骨干区域(14-20%)更大。通过整合矿物质分布图来估计由哺乳引起的股骨总骨矿物质的变化。通过该方法测定的 28% 的较低骨矿物质与根据股骨干重测量测定的 27% 的差异非常一致。除 2 个最远端部位外,单个股骨 10 次重新定位的测量重复性均在 4% 以内。估计总骨矿物质的变化为 1.3%。
The distribution of bone mineral in excised femurs from lactating and nonlactating control rats was localized and quantitated using single photon absorptiometry. Bone mineral content was measured proximodistally in nine sequential 0.32 cm increments along the femur length and then plotted as a function of the distance from the proximal end of the femur. The plots described a mineral distribution profile and revealed that bone loss following lactation was site specific, being greater in the metaphyseal regions (23–36%) than in the diaphyseal area (14–20%). The change in total bone mineral of femur caused by lactation was estimated by integrating the mineral distribution profile plots. The 28% lower bone mineral determined by this method was in close agreement with the 27% difference determined from femur dry weight measurements. Reproducibility of measurements with 10 repositionings of a single femur was within 4% at all but the 2 most distal sites. Variation in the estimated total bone mineral was 1.3%.
使用伽玛相机进行高分辨率骨矿物质密度测量。
DOI: 10.1088/0031-9155/29/1/003
发表时间: 1984
影响因子: 3.5
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DOI: 10.1038/267630a0
发表时间: 1977-01-01
期刊: NATURE
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DOI: 10.2214/ajr.126.6.1313
发表时间: 1976
期刊: AJR. American journal of roentgenology
影响因子: --
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DOI: --
发表时间: 1952
影响因子: 3.6
作者:
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通讯作者: M. H. Quenouille