Maternal outcomes and follow-up after gestational diabetes mellitus.
Maternal outcomes and follow-up after gestational diabetes mellitus.
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DOI：
10.1111/dme.12382
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发表时间：
2014-03
期刊：
影响因子：
--
通讯作者：
Kim C
中科院分区：
文献类型：
--
作者：
Kim C
妊娠期糖尿病反映了母体胰岛素分泌相对于妊娠前需求的受损，以及胎盘和胎儿施加的暂时代谢应激因素。因此，分娩后，患有妊娠糖尿病的妇女患糖尿病和复发性妊娠糖尿病的风险增加，因为其潜在的损害，这可能会进一步加剧怀孕期间的脂肪堆积和产后生活方式行为的恶化。更详细地讨论了这一假设模型，特别是关于妊娠作为β细胞下降的加速剂和妊娠期体重增加的作用的不确定性。该报告还提供了未来葡萄糖耐受不良和糖尿病的风险估计，并审查了可改变的风险因素，特别是体重和生活方式的改变，包括减肥和母乳喂养。还讨论了不可改变的风险因素，如种族/民族和妊娠期间的胰岛素使用。该综述总结了目前关于生活方式改变的文献，产后血糖筛查的建议以及预防孕产妇疾病的未来研究方向。
Gestational diabetes mellitus reflects impaired maternal insulin secretion relative to demand prior to pregnancy, as well as temporary metabolic stressors imposed by the placenta and fetus. Thus, after delivery, women with gestational diabetes have increased risk of diabetes and recurrent gestational diabetes because of their underlying impairment, which may be further exacerbated by fat accretion during pregnancy and post-partum deterioration in lifestyle behaviours. This hypothetical model is discussed in greater detail, particularly the uncertainty regarding pregnancy as an accelerator of β-cell decline and the role of gestational weight gain. This report also presents risk estimates for future glucose intolerance and diabetes and reviews modifiable risk factors, particularly body mass and lifestyle alterations, including weight loss and breastfeeding. Non-modifiable risk factors such as race/ethnicity and insulin use during pregnancy are also discussed. The review concludes with current literature on lifestyle modification, recommendations for post-partum glucose screening, and future directions for research to prevent maternal disease.
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影响因子：
3
作者：
Cheung, NW;Helmink, D
通讯作者：
Helmink, D
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影响因子：
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作者：
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通讯作者：
Clark, Jeanne M.
影响因子：
16.2
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影响因子：
3.3
作者：
Ferrara, Assiamira;Ehrlich, Samantha F.
通讯作者：
Ehrlich, Samantha F.
影响因子：
7.2
作者：
Ehrlich SF;Hedderson MM;Feng J;Davenport ER;Gunderson EP;Ferrara A
通讯作者：
Ferrara A