New molecular imaging targets to characterize myocardial biology.
New molecular imaging targets to characterize myocardial biology.
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DOI:
10.1016/j.ccl.2008.12.008
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发表时间:
2009-05
影响因子:
2.4
通讯作者:
Sinusas AJ
中科院分区:
文献类型:
--
作者:
Morrison AR;Sinusas AJ
Molecular imaging represents a targeted approach to non-invasively assess biologic (both physiologic and pathologic) processes in vivo. Ideally the goal of molecular imaging is not just to provide diagnostic and prognostic information based on identification of the molecular events associated with a pathological process, but rather to guide individually tailored pharmacological, cell-based or genetic therapeutic regimens. This article reviews the recent advances in myocardial molecular imaging in the context of the cardiovascular processes of angiogenesis, apoptosis, inflammation and ventricular remodeling. The focus is on radiotracer-based SPECT and PET molecular imaging approaches.
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