New molecular imaging targets to characterize myocardial biology.

New molecular imaging targets to characterize myocardial biology.
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DOI:
10.1016/j.ccl.2008.12.008
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发表时间:
2009-05
期刊:
影响因子:
2.4
通讯作者:
Sinusas AJ
Sinusas AJ
中科院分区:
医学4区
文献类型:
--
作者:
Morrison AR;Sinusas AJ

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分子成像是一种非侵入性评估体内生物(生理和病理)过程的靶向方法。理想情况下,分子成像的目标不仅仅是基于与病理过程相关的分子事件的鉴定来提供诊断和预后信息,而是指导个体定制的药理学、基于细胞或遗传治疗方案。本文综述了近年来心肌分子影像学在血管生成、细胞凋亡、炎症和心室重构等心血管过程中的研究进展。重点是基于放射性示踪剂的SPECT和PET分子成像方法。
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