The Role of Targeted Temperature Management in Adult Patients Resuscitated from Nonshockable Cardiac Arrests: An Updated Systematic Review and Meta-Analysis.
The Role of Targeted Temperature Management in Adult Patients Resuscitated from Nonshockable Cardiac Arrests: An Updated Systematic Review and Meta-Analysis.
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DOI：
10.1155/2016/2350974
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发表时间：
2016
影响因子：
--
通讯作者：
Li Y
中科院分区：
文献类型：
--
作者：
Song L;Wei L;Zhang L;Lu Y;Wang K;Li Y
Routine targeted temperature management is recommended for comatose adult patients with return of spontaneous circulation after cardiac arrest. However, the role of targeted temperature management in patients resuscitated from nonshockable cardiac arrests remains uncertain. We conducted an updated systematic review and meta-analysis to evaluate the effects of targeted temperature management in this population. Medline, EMBASE, and Cochrane databases were systematically reviewed for studies published between January 2005 and March 2016, in which targeted temperature management was compared with standard care or normothermia for adult patients resuscitated from nonshockable cardiac arrests. A total of 25 trials that included 5715 patients were identified from 10985 relevant papers. Pooled data showed that targeted temperature management not only associated with improved short-term survival (RR = 1.42, 95% CI: 1.28–1.57) and neurological function (RR = 1.63, 95% CI: 1.39–1.91) but also associated with improved long-term survival (RR = 1.64, 95% CI: 1.27–2.12) and neurological recovery (RR = 1.42, 95% CI: 1.07–1.90) in observational cohort studies. However, more frequent infectious complications were reported in hypothermia-treated patients (RR = 1.46, 95% CI: 1.26–1.70) and the quality of the evidence ranged from moderate to very low.
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DOI：
10.1136/bmj.b2535
发表时间：
2009-07-21
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Moher D;Liberati A;Tetzlaff J;Altman DG;PRISMA Group
通讯作者：
PRISMA Group
影响因子：
8.8
作者：
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通讯作者：
Arrich, Jasmin
DOI：
10.1007/s00390-007-0775-9
发表时间：
2007-06-01
期刊：
Intensivmedizin und Notfallmedizin
影响因子：
--
作者：
Heer, C.
通讯作者：
Heer, C.
影响因子：
8.3
作者：
Holzer, Michael;Muellner, Marcus;Laggner, Anton N.
通讯作者：
Laggner, Anton N.
影响因子：
6.5
作者：
Kim, Young-Min;Yim, Hyeon-Woo;Callaway, Clifton W.
通讯作者：
Callaway, Clifton W.