Blood transfusion risk prediction in spinal tuberculosis surgery: development and assessment of a novel predictive nomogram.
Blood transfusion risk prediction in spinal tuberculosis surgery: development and assessment of a novel predictive nomogram.
复制标题
脊柱结核手术中的输血风险预测：新型预测列线图的开发和评估
DOI：
10.1186/s12891-022-05132-z
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发表时间：
2022-02-25
影响因子：
2.3
通讯作者：
Zhan X
中科院分区：
文献类型：
--
作者：
Chen L;Gan Z;Huang S;Liang T;Sun X;Yi M;Wu S;Fan B;Chen J;Chen T;Ye Z;Chen W;Li H;Jiang J;Guo H;Yao Y;Liao S;Yu C;Liu C;Zhan X
本研究试图通过使用一种新的预测列线图来预测脊柱结核手术中的输血风险。本研究对2012年6月至2021年6月在我院行脊柱结核手术的495例患者（输血组167例，非输血组328例）的临床资料进行研究。采用最小绝对收缩和选择算子（LASSO）和多变量Logistic回归分析筛选出具有统计学意义的参数，并将其纳入建立新的预测诺模图模型。采用受试者工作特征曲线（ROC）、校正曲线、C指数和决策曲线分析（DCA）对模型进行评价。最后，通过内部验证进一步评估诺模图。列线图的C指数为0.787（95%置信区间：74.6%-.82.8%）。通过内部验证计算的C值为0.763。预测列线图的曲线下面积（AUC）为0.785，DCA为0.01-0.79。本研究建立了一个具有较高准确性、临床有效性和可靠性的诺模图，用于预测脊柱结核手术中的输血风险。外科医生必须准备术前手术策略，并确保术前有足够的血液供应。
The present study attempted to predict blood transfusion risk in spinal tuberculosis surgery by using a novel predictive nomogram. The study was conducted on the clinical data of 495 patients (167 patients in the transfusion group and 328 patients in the non-transfusion group) who underwent spinal tuberculosis surgery in our hospital from June 2012 to June 2021. The least absolute shrinkage and selection operator (LASSO) and multivariable logistic regression analyses were used to screen out statistically significant parameters, which were included to establish a novel predictive nomogram model. The receiver operating characteristic (ROC) curve, calibration curves, C-index, and decision curve analysis (DCA) were used to evaluate the model. Finally, the nomogram was further assessed through internal validation. The C-index of the nomogram was 0.787 (95% confidence interval: 74.6%–.82.8%). The C-value calculated by internal validation was 0.763. The area under the curve (AUC) of the predictive nomogram was 0.785, and the DCA was 0.01–0.79. A nomogram with high accuracy, clinical validity, and reliability was established to predict blood transfusion risk in spinal tuberculosis surgery. Surgeons must prepare preoperative surgical strategies and ensure adequate availability of blood before surgery.
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影响因子：
2
作者：
Jones JJ;Mundy LM;Blackman N;Shwarz M
通讯作者：
Shwarz M
影响因子：
2.6
作者：
Bian FC;Cheng XK;An YS
通讯作者：
An YS
影响因子：
3.9
作者：
Engel D;Beilstein CM;Jerney P;Furrer MA;Burkhard FC;Löffel LM;Wuethrich PY
通讯作者：
Wuethrich PY
影响因子：
3
作者：
Moon, MS
通讯作者：
Moon, MS
影响因子：
3.5
作者：
Cao, Guorui;Huang, Zeyu;Pei, Fuxing
通讯作者：
Pei, Fuxing