Onset of spermatozoal degeneration in low-fertility Delaware roosters and test for autoimmune basis.
Onset of spermatozoal degeneration in low-fertility Delaware roosters and test for autoimmune basis.
复制标题
低生育力特拉华公鸡精子变性的发生和自身免疫基础测试。
作者：
D. Froman;John D. Kirby;Rita M. Lawler;Paul E. Bernier
本研究的目的是：1）确定公鸡遗传性生殖疾病的发作，其特征是输精管内广泛的精子变性，2）确定自身免疫是否与精子变性相关。75%的受影响公鸡在20周龄时没有射出大比例的退化精子，大约是性成熟的年龄。相反，精液质量在接下来的6周逐渐下降，因为射精量和精子数量都增加了。睾丸和流出道组织通过免疫荧光评价未能揭示与精子相关的IgY或伊加。虽然组织学检查显示近端输精管中淋巴细胞数量较多（P <0.05），但这些细胞与精子或精子凝集无关。虽然精子变性往往是潜伏在精液生产的开始，它似乎不是由于精子自身免疫。
The objectives of this study were 1) to determine the onset of a heritable reproductive disorder in the rooster that is characterized by extensive spermatozoal degeneration within the ductus deferens, and 2) to determine if autoimmunity was associated with spermatozoal degeneration. Seventy-five percent of the affected roosters did not ejaculate large percentages of degenerate spermatozoa at 20 wk of age, approximately the age of sexual maturity. Rather, seminal quality gradually declined over the next 6 wk, as both ejaculate volume and number of spermatozoa ejaculated increased. The evaluation of testicular and excurrent duct tissues via immunofluorescence failed to reveal either IgY or IgA associated with spermatozoa. While histological examination revealed greater lymphocyte numbers (P less than .05) in the proximal ductus deferens, these cells were not associated with spermatozoa nor spermatozoal clumping. While spermatozoal degeneration tends to be latent at the onset of semen production, it does not appear to be due to spermatozoal autoimmunity.
影响因子：
56.9
作者：
GILOH, H;SEDAT, JW
通讯作者：
SEDAT, JW