Associations between Conventional and Emerging Indicators of Dietary Carbohydrate Quality and New-Onset Type 2 Diabetes Mellitus in Chinese Adults.
Associations between Conventional and Emerging Indicators of Dietary Carbohydrate Quality and New-Onset Type 2 Diabetes Mellitus in Chinese Adults.
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中国成人膳食碳水化合物质量的传统指标和新兴指标与新发 2 型糖尿病之间的关联
DOI：
10.3390/nu15030647
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发表时间：
2023-01-27
期刊：
影响因子：
5.9
通讯作者：
Meng, Huicui
中科院分区：
文献类型：
--
作者：
Cui, Zhixin;Wu, Man;Liu, Ke;Wang, Yin;Kang, Tong;Meng, Shuangli;Meng, Huicui
关键词：
膳食血糖指数（GI）、碳水化合物与纤维的比率（CF）和碳水化合物质量指数（CQI）是碳水化合物质量的常规和新兴指标。我们的目的是调查这些指标与中国成年人新发2型糖尿病（T2 DM）风险之间的关系。这项前瞻性队列研究纳入了来自中国健康与营养调查的14，590名基线时无心脏代谢疾病的成年人。采用考克斯比例风险回归分析评估饮食GI、CF和CQI与T2 DM风险之间的关联，并采用限制性三次样条和阈值分析探索剂量-反应关系。平均随访10年后，共发生1053例新发T2 DM病例。饮食GI和CF与T2 DM风险之间存在U形关联（均为P-非线性< 0.0001），当饮食GI为72.85（71.40，74.05）和CF为20.55（17.92，21.91）时，T2 DM风险最低（均为P-对数似然比< 0.0001）。CQI与T2 DM风险之间的负相关性在< 60岁或就读中学或以上的参与者中特别存在（均P趋势< 0.05）。这些结果表明，适度的饮食GI和CF范围和较高的饮食CQI评分可能是中国成年人预防T2 DM的建议。
Dietary glycemic index (GI), carbohydrate to fiber ratio (CF) and carbohydrate quality index (CQI) are conventional and emerging indicators for carbohydrate quality. We aimed to investigate the associations between these indicators and new-onset type 2 diabetes mellitus (T2DM) risk among Chinese adults. This prospective cohort study included 14,590 adults from the China Health and Nutrition Survey without cardiometabolic diseases at baseline. The associations between dietary GI, CF and CQI and T2DM risk were assessed using Cox proportional hazard regression analysis and dose–response relationships were explored using restricted cubic spline and threshold analysis. After a mean follow-up duration of 10 years, a total of 1053 new-onset T2DM cases occurred. There were U-shaped associations between dietary GI and CF and T2DM risk (both P-nonlinear < 0.0001), and T2DM risk was lowest when dietary GI was 72.85 (71.40, 74.05) and CF was 20.55 (17.92, 21.91), respectively (both P-log likelihood ratio < 0.0001). Inverse associations between CQI and T2DM risk specifically existed in participants < 60 y or attended middle school or above (both P-trend < 0.05). These findings indicated that moderate dietary GI and CF range and a higher dietary CQI score may be suggested for T2DM prevention in Chinese adults.
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影响因子：
7.1
作者：
AlEssa, Hala B.;Bhupathiraju, Shilpa N.;Hu, Frank B.
通讯作者：
Hu, Frank B.
影响因子：
16.2
作者：
American Diabetes Association
通讯作者：
American Diabetes Association
DOI：
10.3390/ijerph16071290
发表时间：
2019-04-01
影响因子：
--
作者：
Hu, Yichun;Li, Min;Yang, Xiaoguang
通讯作者：
Yang, Xiaoguang
影响因子：
16.2
作者：
Greenwood DC;Threapleton DE;Evans CE;Cleghorn CL;Nykjaer C;Woodhead C;Burley VJ
通讯作者：
Burley VJ
饮食血糖指数标签：全球视角。
影响因子：
5.9
作者：
Barclay AW;Augustin LSA;Brighenti F;Delport E;Henry CJ;Sievenpiper JL;Usic K;Yuexin Y;Zurbau A;Wolever TMS;Astrup A;Bulló M;Buyken A;Ceriello A;Ellis PR;Vanginkel MA;Kendall CWC;La Vecchia C;Livesey G;Poli A;Riccardi G;Salas-Salvadó J;Trichopoulou A;Bhaskaran K;Jenkins DJA;Willett WC;Brand-Miller JC
通讯作者：
Brand-Miller JC