Precision mapping and transcranial magnetic stimulation of individual-specific functional brain networks in humans.

Precision mapping and transcranial magnetic stimulation of individual-specific functional brain networks in humans.
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DOI:
10.1016/j.xpro.2023.102118
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发表时间:
2023-03-17
期刊:
影响因子:
--
通讯作者:
Liston C
Liston C
中科院分区:
其他
文献类型:
--
作者:
Lynch CJ;Elbau IG;Zhu S;Ayaz A;Bukhari H;Power JD;Liston C

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经颅磁刺激方案中的空间靶向通常不能解释个体人脑的特异质功能组织。在这里,我们提供了一个协议,用于实现有针对性的功能网络刺激(TANS),这占每个人的独特的功能神经解剖和皮质折叠模式。使用示例数据集,我们描述了如何创建头部模型并估计最佳线圈放置和刺激强度,以最大限度地减少脱靶效应。有关本方案使用和执行的完整详细信息,请参见Lynch等人。(2022年)。个体特异性功能网络的选择性刺激方案通过靶向功能网络刺激(TANS)提高刺激特异性使用示例精确功能映射数据集实施TANS的代码寻找最佳线圈放置和估计最佳刺激剂量的步骤出版商说明:进行任何实验方案都需要遵守当地机构的实验室安全和伦理指南。经颅磁刺激方案中的空间靶向通常不能解释个体人脑的特异质功能组织。在这里,我们提供了一个协议,用于实现有针对性的功能网络刺激,这占每个人的独特的功能神经解剖和皮质折叠模式。使用示例数据集,我们描述了如何创建头部模型并估计最佳线圈放置和刺激强度,以最大限度地减少脱靶效应。
Spatial targeting in transcranial magnetic stimulation protocols does not typically account for the idiosyncratic functional organization of individual human brains. Here, we provide a protocol for implementing targeted functional network stimulation (TANS), which accounts for each individual’s unique functional neuroanatomy and cortical folding patterns. Using an example dataset, we describe how to create a head model and estimate the best coil placement and stimulation intensity to minimize off-target effects. For complete details on the use and execution of this protocol, please refer to Lynch et al. (2022). Protocol for selective stimulation of individual-specific functional networks Improved stimulation specificity with atargeted functional network stimulation (TANS) Code for implementing TANS with an example precision functional mapping dataset Steps for finding the best coil placement and estimation of the optimal stimulation dose Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics. Spatial targeting in transcranial magnetic stimulation protocols does not typically account for the idiosyncratic functional organization of individual human brains. Here, we provide a protocol for implementing targeted functional network stimulation, which accounts for each individual’s unique functional neuroanatomy and cortical folding patterns. Using an example dataset, we describe how to create a head model and estimate the best coil placement and stimulation intensity to minimize off-target effects.
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