Evolution and public health

Evolution and public health
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进化与公共卫生

DOI:
10.1073/pnas.0906198106
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发表时间:
2009
期刊:
Proceedings of the National Academy of Sciences
影响因子:
--
通讯作者:
G. Omenn
G. Omenn
中科院分区:
--
文献类型:
--
作者:
G. Omenn

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进化及其自然选择、人口迁移、遗传漂变和创始人效应等要素塑造了我们从事公共卫生工作的世界。人类文化和技术改变了这个星球上的生命,并与无数其他物种共同进化,包括微生物;植物和动物食物来源;疾病的无脊椎媒介;以及鸟类,哺乳动物和非人类灵长类动物之间的中间宿主。对传染性病原体或饮食的不同抗性或易感性的分子机制已经进化,并正在用现代方法发现。其中一些进化关系需要数万年的视角,而其他变化则可以在真实的时间中观察到。进化理解的含义和应用对我们目前的传染病监测,基因-环境相互作用和全球健康差异的计划和政策非常重要。
Evolution and its elements of natural selection, population migration, genetic drift, and founder effects have shaped the world in which we practice public health. Human cultures and technologies have modified life on this planet and have coevolved with myriad other species, including microorganisms; plant and animal sources of food; invertebrate vectors of disease; and intermediate hosts among birds, mammals, and nonhuman primates. Molecular mechanisms of differential resistance or susceptibility to infectious agents or diets have evolved and are being discovered with modern methods. Some of these evolutionary relations require a perspective of tens of thousands of years, whereas other changes are observable in real time. The implications and applications of evolutionary understanding are important to our current programs and policies for infectious disease surveillance, gene–environment interactions, and health disparities globally.
DOI: 10.1126/science.7524148
发表时间: 1994-10-07
期刊: SCIENCE
影响因子: 56.9
作者:
GABRIEL, SE;BRIGMAN, KN;STUTTS, MJ
通讯作者: STUTTS, MJ
DOI: 10.1056/nejm199605023341802
发表时间: 1996-05-02
影响因子: 158.5
作者:
Omenn, GS;Goodman, GE;Hammar, S
通讯作者: Hammar, S
煮熟的红肉、吸烟以及快速 N-乙酰转移酶 2 和 CYP1A2 表型的综合作用会增加结直肠癌的风险。
DOI: --
发表时间: 2001
期刊: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子: --
作者:
LeMarchand,L;Hankin,JH;Wilkens,LR;Pierce,LM;Franke,A;Kolonel,LN;Seifried,A;Custer,LJ;Chang,W;Lum-Jones,A;Donlon,T
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