High frequency ultrasound sacral images in the critically ill: Tissue characteristics versus visual evaluation.

High frequency ultrasound sacral images in the critically ill: Tissue characteristics versus visual evaluation.
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DOI:
10.1016/j.iccn.2017.02.001
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发表时间:
2017-10
影响因子:
5.3
通讯作者:
Munro CL
Munro CL
中科院分区:
医学2区
文献类型:
--
作者:
Grap MJ;Schubert CM;Burk RS;Lucas V;Wetzel PA;Pepperl A;Munro CL

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高频超声(HFUS)系统可以识别组织损伤。我们比较了高频超声组织特征(真皮厚度和真皮密度)与视觉图像检查。在气道插管后24小时内入组的3个ICU(外科创伤、医学呼吸、神经科学)的重症机械通气成人中进行的纵向研究。每天获取骶骨高频超声图像,持续7天。完成了每天最佳图像的专家评估,并与HFUS生成的组织特征(真皮厚度和真皮密度)进行了比较。在113名受试者中,分析了1614项比较,73.2%至84%正常,6.3%至11.8%的比较存在损伤,但观察到的损伤没有变化。损伤类型和平均真皮厚度(p = 0.6645)或真皮中位强度(调整后p = 0.06-0.17)之间的一天比较无显著差异。所有其他日间比较同样不显著。我们没有发现真皮密度,真皮厚度和骶骨HFUS图像变化的目视检查之间的任何日常比较。骶骨高频超声作为组织损伤发展的筛查工具的应用尚处于起步阶段。应进行额外的比较研究,以确定其未来的临床实用性。
High frequency ultrasound (HFUS) systems may identify tissue injury. We compared HFUS tissue characteristics (dermal thickness and dermal density) with visual image examination. Longitudinal study in critically ill mechanically ventilated adults, from 3 ICUs (Surgical Trauma, Medical Respiratory, Neuroscience) enrolled within 24 hours of airway intubation. Sacral HFUS images were obtained daily for up to 7 days. Expert evaluation of the best image per day was completed and compared to HFUS generated tissue characteristics (dermal thickness and dermal density). Of the113 subjects with 1614 comparisons analyzed, 73.2% to 84% were normal, and 6.3% to 11.8% of the comparisons had injury present but no change was noted in the injury observed. There were no significant differences in one-day comparisons among type of injury and mean dermal thickness (p = 0.6645) or dermal median intensity (adjusted p = 0.06–0.17). All other day-to-day comparisons were similarly non-significant. We found no association among dermal density, dermal thickness and visual examination of changes in sacral HFUS images for any day-to-day comparison. The use of sacral HFUS as a screening tool for the development of tissue injury is in its infancy. Additional comparative studies should be conducted to identify its future clinical usefulness.
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