Segmented 2D‐selective RF excitations with weighted averaging and flip angle adaptation for MR spectroscopy of irregularly shaped voxel

Segmented 2D‐selective RF excitations with weighted averaging and flip angle adaptation for MR spectroscopy of irregularly shaped voxel
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分段 2D 选择性 RF 激励,具有加权平均和翻转角自适应,适用于不规则形状体素的 MR 波谱

DOI:
10.1002/mrm.22806
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发表时间:
2011
影响因子:
3.3
通讯作者:
Busch MG
Busch MG
中科院分区:
医学3区
文献类型:
--
作者:
Finsterbusch J;Busch MG

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针对分段二维选择性射频激励,提出了一种具有翻转角自适应的加权平均方法,并将其应用于平面弹道的单线段。覆盖中央间隙的段,即那些具有显著信号贡献的段,比具有低RF幅度和较小信号贡献的(外部)段更频繁地被平均。为了补偿,这些外部段被施加增加的RF幅度,即更大的翻转角度,使得在减少的激发次数中获得未改变的信号贡献。在幻影和活体人脑中的数值模拟和实验表明,该方法在不引入轮廓失真的情况下,显著地提高了信号效率,即每时间单位累积的信号。由于对目标体积的最佳覆盖,它在单体素MR波谱中的应用产生了比基于横截面RF刺激的传统定位更高的信号幅度。因此,该方法可以提高单体素磁共振波谱的可靠性。Magn Reson Med,2011。©2011 Wiley-Liss,Inc.
A weighted averaging scheme with flip angle adaptation is presented for segmented 2D‐selective RF excitations and applied to single‐line segments of a blipped‐planar trajectory. Segments covering the centralk‐space, i.e. those with significant signal contributions, are averaged more often than the (outer) segments with low RF amplitudes and minor signal contributions. For compensation, these outer segments are applied with an increased RF amplitude, i.e. a larger flip angle, such that an unaltered signal contribution is obtained in a reduced number of shots. Numerical simulations and experiments in phantoms and the human brain in vivo demonstrate that the approach considerably increases the signal efficiency, i.e. the signal accumulated per time unit, without introducing profile distortions. Its application to single‐voxel MR spectroscopy of a corpus‐callosum‐shaped region‐of‐interest yielded, due to an optimum coverage of the target volume, higher signal amplitudes than conventional localization based on cross‐sectional RF excitations. Thus, the approach could improve the reliability of single‐voxel MR spectroscopy. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.
使用受激回波进行局部成像。
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Mills,P;Chew,W;Litt,L;Moseley,M
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