Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinoma
Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinoma
复制标题
核糖体蛋白:深入了解肝细胞癌中的分子作用和功能
作者:
Xie X;Guo P;Yu H;Wang Y;Chen G
Ribosomes, which are important sites for the synthesis of proteins related to expression and transmission of genetic information in humans, have a complex structure and diverse functions. They consist of a variety of ribosomal proteins (RPs), ribosomal RNAs (rRNAs) and small nucleolar RNAs. Owing to the involvement of ribosomes in many important biological processes of cells, their major components, rRNAs and RPs, have an important role in human diseases, including the initiation and evolvement of malignancies. However, the main mechanisms underlying the involvement of ribosomes in cancer remain unclear. This review describes the crucial role of ribosomes in various common malignant tumors; in particular, it examines the effects of RPs, including S6, the receptor for activated C-kinase and RPS15A, on the development and progression of hepatocellular carcinoma.
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影响因子:
2
作者:
R. Dmochowski
通讯作者:
R. Dmochowski
影响因子:
8
作者:
Hagner, P. R.;Mazan-Mamczarz, K.;Dai, B.;Balzer, E. M.;Corl, S.;Martin, S. S.;Zhao, X. F.;Gartenhaus, R. B.
通讯作者:
Gartenhaus, R. B.
DOI:
10.1016/j.respe.2020.09.004
发表时间:
2020-10-10
期刊:
Revue D'Epidemiologie et De Sante Publique
影响因子:
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作者:
La rédaction
通讯作者:
La rédaction
影响因子:
9.3
作者:
通讯作者:
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