Functional magnetic resonance imaging study comparing rhythmic finger tapping in children and adults.
Functional magnetic resonance imaging study comparing rhythmic finger tapping in children and adults.
复制标题
DOI：
10.1016/j.pediatrneurol.2011.11.019
复制
发表时间：
2012-02
影响因子：
3.8
通讯作者：
Meintjes EM
中科院分区：
文献类型：
--
作者：
De Guio F;Jacobson SW;Molteno CD;Jacobson JL;Meintjes EM
This study compared brain activations during unpaced rhythmic finger tapping in 12-year old children with those of adults. The subject pressed a button at a pace initially indicated by a metronome (12 consecutive tones) and then continued for 16 seconds of unpaced tapping to provide an assessment of his/her ability to maintain a steady rhythm. In particular, the analyses focused on the superior vermis of the cerebellum, which is known to play a key role in timing. 12 adults and 12 children performed this rhythmic finger tapping task in a 3T scanner. Whole-brain analyses were performed in Brain Voyager with a random effects analysis of variance using the general linear model. A dedicated cerebellar atlas was used to localise cerebellar activations. As in adults, unpaced rhythmic finger tapping in children showed activations in the primary motor cortex, premotor cortex, and cerebellum. However, overall activation was different in that adults showed much more deactivation in response to the task, particularly in the occipital and frontal cortex. The other main differences were additional recruitment of motor and premotor areas in children compared to adults along with increased activity in the vermal region of the cerebellum. These findings suggest that the timing component of the unpaced rhythmic finger tapping task is less efficient and automatic in children, who needed to recruit the superior vermis more intensively to maintain the rhythm, even though they performed somewhat more poorly than the adults.
登录
查看更多内容
影响因子：
3.2
作者：
Harrington, DL;Rao, SM;Cox, RW
通讯作者：
Cox, RW
影响因子：
5.7
作者：
Diedrichsen, Joern;Balsters, Joshua H.;Ramnani, Narender
通讯作者：
Ramnani, Narender
影响因子：
2.5
作者：
Meintjes, Ernesta M.;Jacobson, Sandra W.;Molteno, Christopher D.;Gatenby, J. Christopher;Warton, Christopher;Cannistraci, Christopher J.;Gore, John C.;Jacobson, Joseph L.
通讯作者：
Jacobson, Joseph L.
影响因子：
29.3
作者：
GOLDBERG, G
通讯作者：
GOLDBERG, G
影响因子：
2.6
作者：
Lewis, PA;Wing, AM;Miall, RC
通讯作者：
Miall, RC