Posterior Corneal Characteristics of Cataract Patients with High Myopia.
Posterior Corneal Characteristics of Cataract Patients with High Myopia.
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高度近视白内障患者后角膜特征
DOI：
10.1371/journal.pone.0162012
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Jiang Y
中科院分区：
文献类型：
--
作者：
Jing Q;Tang Y;Qian D;Lu Y;Jiang Y
目的探讨高度近视患者白内障手术前角膜后表面的特征。方法在复旦大学附属眼耳鼻喉科医院进行横断面研究。高度近视组167眼（眼轴长度≥ 26 mm），对照组150眼（眼轴长度> 20 mm且< 25 mm），采用旋转Scheimpflug相机（Pentacam）和部分相干干涉仪（IOLMaster）测量角膜散光和眼轴长度。结果高度近视组角膜总散光和角膜前壁散光值均高于对照组。高度近视研究组与对照组之间的角膜后散光无显著差异。在研究组中，平均后角膜散光（范围0 - −0.9屈光度）为-0.29屈光度（D）± 0.17标准差（SD）。角膜后表面87.43%的眼角膜子午线垂直（60° ~ 120 °），不随年龄增长而改变。角膜后散光与角膜前散光之间存在显著相关性（r = 0.235，p = 0.002），尤其是当角膜前表面显示符合规则（WTR）散光时（r = 0.452，p = 0.000）。高度近视组角膜后散光与年龄呈弱负相关（r =-0.15，p = 0.053）。与总角膜散光值相比，前角膜测量在68.75%的眼中高估了WTR散光，平均高估0.27 ± 0.18 D，在88.89%的眼中低估了ATR散光，平均低估0.41 ± 0.28 D，63.64%的眼低估了斜向散光，平均为0.24 ± 0.13D。结论高度近视眼角膜后壁散光随年龄增长而逐渐减小，并以ATR散光为主。当角膜前散光为WTR时，角膜后散光与角膜前散光有显著相关性。如果在为高度近视患者选择散光矫正型人工晶状体时未考虑角膜后散光，则单独使用角膜前散光测量将导致高估WTR散光，低估ATR和斜散光。
Purpose To evaluate the characteristics of the posterior corneal surface in patients with high myopia before cataract surgery. Methods We performed a cross-sectional study at the Eye and ENT Hospital of Fudan University, Shanghai, China. Corneal astigmatism and axial length were measured with a rotating Scheimpflug camera (Pentacam) and partial coherence interferometry (IOLMaster) in a high-myopia study group of 167 eyes (axial length ≥ 26 mm) and a control group of 150 eyes (axial length > 20 mm and < 25 mm). Results Total corneal astigmatism and anterior corneal astigmatism values were higher in the high-myopia group than in the control group. There was no significant difference in posterior corneal astigmatism between the high-myopia study group and the control group. In the study group, the mean posterior corneal astigmatism (range 0 – −0.9 diopters) was –0.29 diopters (D) ± 0.17 standard deviations (SD). The steep corneal meridian was aligned vertically (60°–120°) in 87.43% of eyes for the posterior corneal surface, and did not change with increasing age. There was a significant correlation (r = 0.235, p = 0.002) between posterior corneal astigmatism and anterior corneal astigmatism, especially when the anterior corneal surface showed with-the-rule (WTR) astigmatism (r = 0.452, p = 0.000). There was a weak negative correlation between posterior corneal astigmatism and age (r = –0.15, p = 0.053) in the high-myopia group. Compared with total corneal astigmatism values, the anterior corneal measurements alone overestimated WTR astigmatism by a mean of 0.27 ± 0.18 D in 68.75% of eyes, underestimated against-the-rule (ATR) astigmatism by a mean of 0.41 ± 0.28 D in 88.89% of eyes, and underestimated oblique astigmatism by a mean of 0.24 ± 0.13 D in 63.64% of eyes. Conclusions Posterior corneal astigmatism decreased with age and remained as ATR astigmatism in most cases of high myopia. There was a significant correlation between posterior corneal astigmatism and anterior corneal astigmatism when anterior corneal astigmatism was WTR. If posterior corneal astigmatism is not accounted for when selecting toric intraocular lenses for high-myopia patients, the use of anterior corneal astigmatism measurements alone will lead to overestimation of WTR astigmatism and underestimation of ATR and oblique astigmatism.
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影响因子：
3.7
作者：
Yin G;Wang YX;Zheng ZY;Yang H;Xu L;Jonas JB;Beijing Eye Study Group
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