Structure of Smooth Muscle

Structure of Smooth Muscle
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平滑肌的结构

DOI:
--
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发表时间:
1985
期刊:
影响因子:
--
通讯作者:
A. Somlyo
A. Somlyo
中科院分区:
--
文献类型:
--
作者:
R. Garfield;A. Somlyo

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了解功能的结构基础是理解生物过程(也许是所有物理过程)的必要先决条件。正如器官生理学跟随解剖学的发展,以及细胞作为器官基本单位的认识是光学显微镜的结果一样,现代细胞生理学的存在很大程度上要归功于电子显微镜和相关学科。在过去的几十年里,平滑肌的电子显微镜揭示了神经肌肉关系、负责细胞间通讯的连接结构、介导收缩的细丝以及参与细胞代谢、调节和复制的细胞内细胞器(综述,参见参考文献14、15、33、42、78、79、84、95、98)。除了传统透射电子显微镜至少部分解决的这些问题之外,与平滑肌中离子分布相关的几个问题也适用于分析电子显微镜:电子探针X射线微量分析(EDS)和电子能量损失光谱(EELS)。这些方法在骨骼肌中的应用对于确定离子(例如 Ca2+、Mg2+)在亚细胞区室之间的运动非常有价值 (87, 96)。
An understanding of the structural bases of function is an essential prerequisite for understanding biological, and perhaps all physical, processes. Just as organ physiology followed the development of anatomy, and the recognition of the cell as the fundamental unit of organs was the result of light microscopy, modern cell physiology owes much of its existence to electron microscopy and allied disciplines. Electron microscopy of smooth muscle, over the last few decades, revealed neuromuscular relationships, junctional structures responsible for cell-to-cell communication, filaments mediating contraction and the intracellular organelles involved in cellular metabolism, regulation and replication (for review, see refs. 14, 15, 33, 42, 78, 79, 84, 95, 98). In addition to these problems solved, at least partially, by conventional transmission electron microscopy, several questions related to the distribution of ions in smooth muscle lend themselves to analytical electron microscopy: electron probe X-ray microanalysis (EDS) and electron energy loss spectroscopy (EELS). The application of these methods to skeletal muscle has been valuable in determining the movement of ions (e.g., Ca2+, Mg2+) between subcellular compartments (87, 96).
生物学中的电子探针和电子能量损失分析。
DOI: 10.1016/0304-3991(82)90290-x
发表时间: 1982
期刊: Ultramicroscopy
影响因子: 2.2
作者:
Somlyo,AP;Shuman,H
通讯作者: Shuman,H
平滑肌中的钙和单价离子。
DOI: --
发表时间: 1982
期刊: Federation proceedings
影响因子: --
作者:
Somlyo,AP;Somlyo,AV;Shuman,H;Endo,M
通讯作者: Endo,M
子宫肌肉中的溶酶体装置:雌激素和卵巢切除术的影响。
DOI: 10.1095/biolreprod23.4.867
发表时间: 1980
影响因子: 3.6
作者:
Sloane,BF
通讯作者: Sloane,BF