Autoregulatory factors of secondary metabolism and morphogenesis in actinomycetes.

Autoregulatory factors of secondary metabolism and morphogenesis in actinomycetes.
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放线菌次生代谢和形态发生的自身调节因素。

DOI:
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发表时间:
1990
影响因子:
9
通讯作者:
T. Beppu
T. Beppu
中科院分区:
工程技术1区
文献类型:
--
作者:
S. Horinouchi;T. Beppu

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革兰氏阳性细菌属链霉菌具有有趣的生物学特性,例如产生多种次生代谢物的能力,以及最终形成孢子的菌丝体形式。次生代谢与细胞分化关系密切,次生代谢可能是细胞分化的一种生理表现。各种可扩散的低分子化学物质通常作为调节因子发挥作用,就像真核生物中的“激素”一样,对次生代谢和细胞分化起作用。在这些因素中,A因子被研究得最广泛。本文就这些调节因子的化学结构、功能、生物合成和作用方式等方面的研究进展作一综述。
The Gram-positive bacterial genus Streptomyces possesses interesting biological aspects, such as the ability to produce a wide variety of secondary metabolites and a mycelial form of growth that culminates in sporulation. A close relationship of secondary metabolism and cell differentiation has been well recognized; secondary metabolism might be a physiological expression of cell differentiation. A variety of diffusible low-molecular-weight chemical substances have been found to function in general as regulatory factors, like "hormones" in eukaryotes, for secondary metabolism and cell differentiation. Among these factors, A-factor has been most extensively studied. This review summarizes recent research on the chemical structures, functions, biosyntheses, and mode of action of these regulatory factors.
DOI: 10.1099/00221287-131-4-833
发表时间: 1985
期刊: Journal of general microbiology
影响因子: --
作者:
Grund,AD;Ensign,JC
通讯作者: Ensign,JC