Oral Metformin and Polymetformin Reprogram Immunosuppressive Microenvironment and Boost Immune Checkpoint Inhibitor Therapy in Colorectal Cancer
Oral Metformin and Polymetformin Reprogram Immunosuppressive Microenvironment and Boost Immune Checkpoint Inhibitor Therapy in Colorectal Cancer
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口服二甲双胍和聚二甲双胍重新编程结直肠癌的免疫抑制微环境并增强免疫检查点抑制剂治疗
DOI:
10.1002/adtp.202000168
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发表时间:
2020-10
影响因子:
4.6
通讯作者:
Leaf Huang
中科院分区:
文献类型:
--
作者:
Yang Xiong;Wantong Song;Limei Shen;Ying Wang;Jing Zhang;Mengying Hu;Yun Liu;Jingjing Li;Sara Musetti;Rihe Liu;Leaf Huang
Immune checkpoint inhibitors (ICI), especially PD‐1/PD‐L1 inhibitors, are emerging as promising therapeutic options for patients with advanced tumors, but the response rate in the majority of colorectal cancer (CRC) patients remains low. Herein, the use o
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影响因子:
2
作者:
R. Dmochowski
通讯作者:
R. Dmochowski
DOI:
10.1016/j.respe.2020.09.004
发表时间:
2020-10-10
期刊:
Revue D'Epidemiologie et De Sante Publique
影响因子:
--
作者:
La rédaction
通讯作者:
La rédaction
影响因子:
9.3
作者:
通讯作者:
--
影响因子:
5.9
作者:
Craighead FL
通讯作者:
Craighead FL