Fibromyalgia and the serotonin pathway.
Fibromyalgia and the serotonin pathway.
复制标题
纤维肌痛和血清素途径。
DOI:
--
复制
发表时间:
1998
期刊:
影响因子:
--
通讯作者:
J. Juhl
中科院分区:
文献类型:
--
作者:
J. Juhl
Fibromyalgia syndrome is a musculoskeletal pain and fatigue disorder manifested by diffuse myalgia, localized areas of tenderness, fatigue, lowered pain thresholds, and nonrestorative sleep. Evidence from multiple sources support the concept of decreased flux through the serotonin pathway in fibromyalgia patients. Serotonin substrate supplementation, via L-tryptophan or 5-hydroxytryptophan (5-HTP), has been shown to improve symptoms of depression, anxiety, insomnia and somatic pains in a variety of patient cohorts. Identification of low serum tryptophan and serotonin levels may be a simple way to identify persons who will respond well to this approach.
DOI:
10.1177/37.7.2471724
发表时间:
1989
期刊:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
影响因子:
--
作者:
McNeill,DL;Westlund,KN;Coggeshall,RE
通讯作者:
Coggeshall,RE
影响因子:
3.5
作者:
Zucker,I
通讯作者:
Zucker,I
DOI:
10.1073/pnas.94.10.5308
发表时间:
1997-05-13
影响因子:
11.1
作者:
Nishizawa, S;Benkelfat, C;Diksic, M
通讯作者:
Diksic, M