Manipulating and assembling metallic beads with Optoelectronic Tweezers.

Manipulating and assembling metallic beads with Optoelectronic Tweezers.
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DOI:
10.1038/srep32840
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发表时间:
2016-09-07
期刊:
影响因子:
4.6
通讯作者:
Neale SL
Neale SL
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Zhang S;Juvert J;Cooper JM;Neale SL

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光电子镊子(OET)或光图案化介电泳法(DEP)是一种用于控制微米和纳米粒子的微操作技术,应用于细胞分选和研究细胞通讯。此外,精确移动小物体并将其组装成任意2D图案的能力也使OET成为微制造应用的一项有吸引力的技术。在这项工作中,我们演示了利用电子捕获技术将直径为50 μm的导电银包覆聚甲基丙烯酸甲酯(PMMA)微球操纵成定制的图案。实验结果表明,微球的最大运动速度可达3200 μm/S,相当于4.2nN牛顿(10−9 N)的DEP力,并可实现高精度的定位。我们的模拟表明,这种强大的DEP力的潜在机制是由于电场和包裹在微球上的银壳之间的相互作用,导致粒子附近的电场显著增加。相关的电场梯度增加导致的DEP力比之前报道的任何OET器件都要强得多,这有助于在不影响定位精度的情况下有效地操纵金属微球,并且对于电子元件组装和电路构建应用非常重要。
Optoelectronic tweezers (OET) or light-patterned dielectrophoresis (DEP) has been developed as a micromanipulation technology for controlling micro- and nano-particles with applications such as cell sorting and studying cell communications. Additionally, the capability of moving small objects accurately and assembling them into arbitrary 2D patterns also makes OET an attractive technology for microfabrication applications. In this work, we demonstrated the use of OET to manipulate conductive silver-coated Poly(methyl methacrylate) (PMMA) microspheres (50 μm diameter) into tailored patterns. It was found that the microspheres could be moved at a max velocity of 3200 μm/s, corresponding to 4.2 nano-newton (10−9 N) DEP force, and also could be positioned with high accuracy via this DEP force. The underlying mechanism for this strong DEP force is shown by our simulations to be caused by a significant increase of the electric field close to the particles, due to the interaction between the field and the silver shells coating the microspheres. The associated increase in electrical gradient causes DEP forces that are much stronger than any previously reported for an OET device, which facilitates manipulation of the metallic microspheres efficiently without compromise in positioning accuracy and is important for applications on electronic component assembling and circuit construction.
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