Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children
Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children
复制标题
芬兰儿童食物消耗与血浆脂肪酸组成和估计去饱和酶活性的横截面关联
DOI：
10.1007/s11745-014-3894-7
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发表时间：
2014
期刊：
影响因子：
1.9
通讯作者：
T. Lakka
中科院分区：
文献类型：
--
作者：
T. Venäläinen;U. Schwab;J. Ågren;V. Mello;V. Lindi;A. Eloranta;S. Kiiskinen;D. Laaksonen;T. Lakka
血浆脂肪酸(FA)组成已知是饮食脂肪质量的一个指标，但其他饮食因素与血浆FA组成之间的关联在儿童中尚不清楚。我们在儿童中调查了食物摄入量与脂肪酸比例的横截面关系，并估计了血浆胆固醇酯(CE)和磷脂(PL)中的去饱和酶活性。受试者是423名6-8岁儿童的人群样本，在体力活动和儿童营养(恐慌症)研究的基线下进行了检查。我们通过食物记录来评估食物的消耗量，用气相色谱来评估血浆FA的组成。我们使用调整了年龄、性别、体力活动和总能量摄入量的线性回归模型来分析这些关联。植物油人造黄油(脂肪60-80%)的摄入量越高，血浆CE和PL中亚油酸和α-亚麻酸的比例就越高。高纤维谷物产品的高消费量与CE和PL中油酸的比例较低有关。糖的摄入量与血浆CE中棕榈油酸和油酸的比例直接相关。植物油人造黄油的摄入量与血浆CE和PL中估计的硬脂酰辅酶A去饱和酶活性呈负相关，而糖果的摄入量与血浆CE中的硬脂酰辅酶A去饱和酶活性呈正相关。我们的研究结果表明，血浆FA成分不仅是反映膳食脂肪质量的生物标志物，而且反映了儿童对高纤维谷物产品和高糖食物的摄入。
Plasma fatty acid (FA) composition is known to be an indicator of dietary fat quality, but the associations of other dietary factors with plasma FA composition remain unknown in children. We investigated the cross-sectional associations of food consumption with the proportions of FA and estimated desaturase activities in plasma cholesteryl esters (CE) and phospholipids (PL) among children. The subjects were a population sample of 423 children aged 6–8 years examined at baseline of The Physical Activity and Nutrition in Children (PANIC) Study. We assessed food consumption by food records and plasma FA composition by gas chromatography. We used linear regression models adjusted for age, sex, physical activity and total energy intake to analyze the associations. A higher consumption of vegetable oil-based margarine (fat 60–80 %) was associated with a higher proportion of linoleic and α-linolenic acids in plasma CE and PL. A higher consumption of high-fiber grain products was related to a lower proportion of oleic acid in CE and PL. The consumption of candy was directly associated with the proportion of palmitoleic and oleic acid in plasma CE. The consumption of vegetable oil-based margarine was inversely associated with estimated stearoyl-CoA-desaturase activity in plasma CE and PL and the consumption of candy was directly related to it in plasma CE. The results of our study suggest that plasma FA composition is not only a biomarker for dietary fat quality but also reflects the consumption of high-fiber grain products and foods high in sugar among children.
影响因子：
7.1
作者：
MA, J;FOLSOM, AR;ECKFELDT, JH
通讯作者：
ECKFELDT, JH