Prevalence, profile and predictors of malnutrition in children with congenital heart defects: a case-control observational study.
Prevalence, profile and predictors of malnutrition in children with congenital heart defects: a case-control observational study.
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DOI：
10.1136/adc.2009.176644
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发表时间：
2011-04
影响因子：
5.2
通讯作者：
Okeiyi JC
中科院分区：
文献类型：
--
作者：
Okoromah CA;Ekure EN;Lesi FE;Okunowo WO;Tijani BO;Okeiyi JC
探讨先天性心脏缺陷（CHDs）患儿严重营养不良的患病率、特点及预测因素。病例对照，观察性研究。尼日利亚拉各斯三级教学医院（2006年3月至2008年3月）。3-192个月的未纠正的症状性冠心病患儿和健康对照者，频率与年龄和性别相匹配。基于WHO/国家卫生统计中心/疾病控制和预防中心的营养不良患病率z评分≤- 2；年龄体重、身高/长度体重和年龄身高；病例组和对照组以及无青紫型和紫绀型冠心病患者体重不足、消瘦和发育迟缓的比例；并使用多变量逻辑分析来预测营养不良。90.4%的病例和21.1%的对照组存在营养不良（p=0.0001）， 61.2%和2.6%的对照组存在严重营养不良（p=0.0001）。消瘦、发育迟缓和体重不足分别占病例和对照组的41.1%、28.8%和20.5%，分别占2.6%、3.9%和14.5%。无青紫型冠心病消瘦率（58.3%）显著高于青紫型冠心病（p=0.0001），发育迟缓率（68.0%）显著高于青紫型冠心病（p=0.0001）。患儿断奶年龄明显低于对照组（分别为3.24±0.88和7.04±3.04个月，p=0.0001），无氰型冠心病明显低于青紫型冠心病（分别为2.14±0.33和5.33±1.22个月，p=0.004）。冠心病营养不良的预测因素包括贫血、中度至重度充血性心力衰竭（CHF）、饮食中脂肪摄入不良和长期未手术的疾病。在这些儿童的CHD术前，伴有贫血和中度至重度CHF的严重营养不良非常普遍。早期断奶可能是心力衰竭患者进食困难的标志。
To investigate the prevalence, profile and predictors of severe malnutrition in children with congenital heart defects (CHDs). Case–control, observational study. Tertiary teaching hospital in Lagos, Nigeria (March 2006 to March 2008). Children aged 3–192 months with uncorrected symptomatic CHD and healthy controls, frequency matched for age and sex. Prevalence of malnutrition based on WHO/National Center for Health Statistics/Centers for Disease Control and Prevention z score ≤−2; weight for age, weight for height/length and height for age; proportions of underweight, wasting and stunting in cases and controls, and in acyanotic and cyanotic CHD; and predictors of malnutrition using multivariate logistic analysis. 90.4% of cases and 21.1% of controls had malnutrition (p=0.0001), and 61.2% and 2.6%, respectively, had severe malnutrition (p=0.0001). Wasting, stunting and underweight were identified in 41.1%, 28.8% and 20.5%, and 2.6%, 3.9% and 14.5% of cases and controls, respectively. Wasting was significantly higher (58.3%) in acyanotic CHD (p=0.0001), and stunting (68.0%) in cyanotic CHD (p=0.0001). Age at weaning was significantly lower in cases than controls (3.24±0.88 and 7.04±3.04 months, respectively; p=0.0001) and in acyanotic than cyanotic CHD (2.14±0.33 and 5.33±1.22 months, respectively; p=0.004). Predictors of malnutrition in CHD were anaemia, moderate to severe congestive heart failure (CHF), poor dietary intake of fat and prolonged unoperated disease. Severe malnutrition in association with anaemia and moderate to severe CHF is highly prevalent in CHD preoperatively in these children. Early weaning may be a marker of feeding difficulties in heart failure.
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影响因子：
3.3
作者：
Man, WDC;Weber, M;Greenwood, BM
通讯作者：
Greenwood, BM
DOI：
10.1016/s0735-1097(03)00256-0
发表时间：
2003-05-07
影响因子：
24
作者：
Al-Attar, I;Orav, J;Lipshultz, SE
通讯作者：
Lipshultz, SE
影响因子：
5.2
作者：
CAMPBELL, M;REYNOLDS, G
通讯作者：
REYNOLDS, G
影响因子：
7.1
作者：
HAMILL, PVV;DRIZD, TA;MOORE, WM
通讯作者：
MOORE, WM
DOI：
10.1097/01.mco.0000165002.08955.5b
发表时间：
2005-05-01
影响因子：
3.1
作者：
Filippatos, GS;Anker, SD;Kremastinos, DT
通讯作者：
Kremastinos, DT