Comparison of Body Mass Index and Waist Circumference in the Prediction of Diabetes: A Retrospective Longitudinal Study.
Comparison of Body Mass Index and Waist Circumference in the Prediction of Diabetes: A Retrospective Longitudinal Study.
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DOI：
10.1007/s13300-021-01138-3
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发表时间：
2021-10
期刊：
影响因子：
--
通讯作者：
Arima H
中科院分区：
文献类型：
--
作者：
Abe M;Fujii H;Funakoshi S;Satoh A;Kawazoe M;Maeda T;Tada K;Yokota S;Yamanokuchi T;Yoshimura C;Mimata R;Takahashi K;Ito K;Yasuno T;Kuga T;Mukoubara S;Akiyoshi K;Kawanami D;Masutani K;Arima H
体重指数(BMI)和腰围指数(WC)都与糖尿病风险有关，它们在预测糖尿病能力方面的差异仍存在争议。我们进行了一项以人群为基础的研究，以调查和比较性别与糖尿病的关系。这项研究共纳入了4754名年龄在40岁至80岁之间、在2008年至2017年期间没有基线糖尿病的受试者。使用多变量COX比例风险模型，我们根据体重指数或腰围的三分位数计算糖尿病的危险比。应用Harrell的C统计量来评估和比较使用BMI和WC的模型的预测能力。体重指数和腰围与糖尿病风险呈显著正相关。在男性中，极端三合一(BMI>； 25.1百万公斤/平方米和WC>； 88.0亿厘米)提供的风险是第一三合一(<； 22.6亿公斤/平方米和<； 81.2百万厘米)的1.58倍或2.04倍。在女性中，体重指数( )24.4g/m2的女性患糖尿病的风险是第一个体重指数(<； )的3.28倍，而WC≥ 78.2 cm患糖尿病的可能性是WC<； 78.2 cm的两倍多。体重指数和腰围在预测男女糖尿病方面的表现相当(男性P值为0.447，女性为0.337)。BMI和WC都显示出与糖尿病的正相关，并提供了男女糖尿病的比较预测性能。男性BMI 25.1 kg/m2和WC 88.0 cm，女性BMI 24.4 kg/m2和WC 78.2 cm，可能有助于制定有效的糖尿病预防策略。
Both body mass index (BMI) and waist circumference (WC) are associated with diabetes risk, and the difference between them in predictive ability for diabetes is still contentious. We conducted a population-based study to investigate and compare the association of them with diabetes by sex. This study included a total of 4754 subjects aged 40–80 years with no diabetes at baseline between 2008 and 2017. Using multivariate Cox proportional hazards models, we calculated hazard ratios for diabetes according to tertiles of BMI or WC. Harrell's C statistics was applied to assess and compare the predictive ability of the models using BMI and WC. Both BMI and WC showed the significant positive trends with diabetes risk. In men, the extreme tertiles (BMI > 25.1 kg/m2 and WC > 88.0 cm) provided 1.58-fold or 2.04-fold higher risk compared with the first tertiles (< 22.6 kg/m2 and < 81.2 cm). In women, BMI > 24.4 kg/m2 showed 3.28-fold higher risk than the first tertile (< 21.6 kg/m2), whereas WC ≥ 78.2 cm was more than twice as likely to suffer from diabetes as WC < 78.2 cm. BMI and WC showed a comparative performance in predicting diabetes in both sexes (P value 0.447 in men, and 0.337 in women). Both BMI and WC showed a positive association with diabetes and offered a comparative predictive performance for diabetes in both sexes. The cut-off points, BMI 25.1 kg/m2 and WC 88.0 cm in men and BMI 24.4 kg/m2 and WC 78.2 cm in women, might contribute to the effective prevention strategies for diabetes.
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影响因子：
3.7
作者：
Fujita M;Sato Y;Nagashima K;Takahashi S;Hata A
通讯作者：
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