Associations of Coexisting Pain and Fatigue Severity with Physical Performance and Quality of Life Among Middle-Aged and Older Individuals with Chronic Knee Pain: Secondary Analysis of a Randomized Clinical Trial.
Associations of Coexisting Pain and Fatigue Severity with Physical Performance and Quality of Life Among Middle-Aged and Older Individuals with Chronic Knee Pain: Secondary Analysis of a Randomized Clinical Trial.
复制标题
DOI：
10.1093/pm/pnab115
复制
发表时间：
2021-11-26
期刊：
影响因子：
3.1
通讯作者：
Murphy, Susan Lynn
中科院分区：
文献类型：
--
作者：
Chen, Yen Tzu;Murphy, Susan Lynn
研究慢性膝关节疼痛患者的疼痛和疲劳严重程度与身体表现和生活质量的关系。横截面。一般社区。成人（N = 193），年龄≥50岁，患有慢性膝关节疼痛。体能测试包括6分钟步行测试、计时起身和行走测试以及20英尺计时步行测试。生活质量（QOL）由医学结局研究简表-12健康调查测量。采用简明疼痛量表（BPI）和简明疲劳量表（BFI）评估疼痛和疲劳。进行多元线性回归分析，以检查共存的疼痛和疲劳的严重程度与体能和生活质量的关联。参与者根据BPI和BFI评分分为四个严重程度组：轻度疼痛/轻度疲劳;中度疼痛/轻度疲劳;轻度疼痛/中度疲劳;中度疼痛/中度疲劳（包括重度疼痛/重度疲劳）。中度疼痛/中度疲劳组在六分钟步行中的身体表现明显较差（标准化β [β] = −0.22，95%置信区间[CI] −0.38至−0.06，P < 0.05）（β = −0.41，95%CI −0.61至−0.20，P < 0.001）和精神生活质量（β = −0.26，95%CI −0.46至−0.07，P < 0.05）高于轻度疼痛/轻度疲劳组。此外，轻度疼痛/中度疲劳组的精神生活质量水平显著低于轻度疼痛/轻度疲劳组（β =-0.27，95%CI-0.44至0.10，P < 0.05）。中度疼痛/轻度疲劳组与轻度疼痛/轻度疲劳组无统计学差异。同时存在中度疼痛和中度疲劳与较差的体能和QOL相关。疲劳导致心理生活质量水平较低。除疼痛外，疲劳的临床评估应作为慢性膝关节疼痛的标准检查。
To examine associations of combined pain and fatigue severity with physical performance and quality of life in people with chronic knee pain. Cross-sectional. General community. Adults (N = 193) ≥50 years of age with chronic knee pain. Physical performance measures included the Six-Minute Walk test, Timed Up and Go test, and 20-foot timed walk test. Quality of life (QOL) was measured by the Medical Outcomes Study Short Form-12 Health Survey. The Brief Pain Inventory (BPI) and Brief Fatigue Inventory (BFI) were used to evaluate pain and fatigue. Multiple linear regression analyses were conducted to examine associations of coexisting pain and fatigue severity with physical performance and QOL. Participants were categorized by BPI and BFI scores into four severity groups: mild pain / mild fatigue; moderate pain / mild fatigue; mild pain / moderate fatigue; and moderate pain / moderate fatigue (which included severe pain / severe fatigue). The moderate pain / moderate fatigue group had significantly worse physical performance on the Six-Minute Walk (standardized beta [β] = −0.22, 95% confidence interval [CI] −0.38 to −0.06, P < 0.05) and poorer physical (β = −0.41, 95% CI −0.61 to −0.20, P < 0.001) and mental QOL (β = −0.26, 95% CI −0.46 to −0.07, P < 0.05) than the mild pain / mild fatigue group. Moreover, the mild pain / moderate fatigue group had significantly lower levels of mental QOL (β = −0.27, 95% CI −0.44 to −0.10, P < 0.05) than those of the mild pain / mild fatigue group. The moderate pain / mild fatigue group did not differ statistically from the mild pain / mild fatigue group. Coexisting moderate pain and moderate fatigue were related to worse physical performance and QOL. Fatigue contributed to lower levels of mental QOL. Clinical assessment of fatigue in addition to pain should be included as a standard examination for chronic knee pain.
登录
查看更多内容
影响因子：
--
作者：
Dunlop, Dorothy D.;Song, Jing;Semanik, Pamela A.;Sharma, Leena;Chang, Rowland W.
通讯作者：
Chang, Rowland W.
影响因子：
2.3
作者：
Murphy SL;Lyden AK;Clary M;Geisser ME;Yung RL;Clauw DJ;Williams DA
通讯作者：
Williams DA
影响因子：
2.2
作者：
Fertelli, Tulay Kars;Tuncay, Fatma Ozkan
通讯作者：
Tuncay, Fatma Ozkan
影响因子：
2.3
作者：
Bedson, John;Croft, Peter R.
通讯作者：
Croft, Peter R.
影响因子：
2.3
作者：
Jinks, Clare;Ong, Bie Nio;Richardson, Jane
通讯作者：
Richardson, Jane