Physical activity levels and functional performance in the osteoarthritis initiative: a graded relationship.
Physical activity levels and functional performance in the osteoarthritis initiative: a graded relationship.
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DOI：
10.1002/art.27760
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发表时间：
2011-01
影响因子：
--
通讯作者：
Chang, Rowland W.
中科院分区：
文献类型：
--
作者：
Dunlop, Dorothy D.;Song, Jing;Semanik, Pamela A.;Sharma, Leena;Chang, Rowland W.
体力活动可以改善患有关节炎的成年人的功能，但尚不清楚与功能益处是否存在分级关系。我们研究了成人膝骨关节炎患者自我报告的体力活动与观察到的功能表现之间的横向和纵向关系。骨关节炎倡议队列包括 2589 名膝骨关节炎患者（其中 2301 名进行了纵向随访），基线年龄为 45 至 79 岁。通过定时 20 米步行测试评估了两年的预期年度功能表现。我们使用线性回归来估计后续功能中体力活动四分位数的差异（基线和 1 年活动分别预测 1 年和 2 年功能），并根据人口统计数据（年龄、性别、种族/民族、教育程度、婚姻状况）和健康因素（骨关节炎严重程度、膝盖症状、膝盖疼痛、膝盖损伤、体重指数、合并症、抑郁、吸烟、饮酒、其他关节疼痛）进行调整。增加体力活动水平与功能表现具有显着的分级关系。体力活动四分位数组中的成年人（从最不活跃到最活跃）的平均步态速度在基线时分别为 4.0、4.2、4.3、4.5 英尺/秒（趋势 p 值 <.001），一年后平均步态速度为 4.1、4.2、4.3、4.5 英尺/秒（趋势 p 值 <.001）；调整协变量后，增加趋势仍然显着。性别和年龄组的研究结果相似。这些前瞻性数据显示，患有膝骨关节炎的成年人的体力活动水平与更好的表现之间存在一致的分级关系。这些发现支持鼓励无法达到最低推荐体力活动的关节炎患者尽可能活跃的指南。
Physical activity improves function for adults with arthritis, but it is unknown if there is a graded relationship with functional benefit. We examine the cross-sectional and longitudinal relationship between self-reported physical activity and observed functional performance in adults with knee osteoarthritis. The Osteoarthritis Initiative cohort included 2589 persons with knee osteoarthritis (2301 having longitudinal follow-up) aged 45 to 79 years at baseline. Two years of prospective annual functional performance was assessed from timed 20 meter walk tests. We used linear regression to estimate differences across physical activity quartiles in subsequent function (baseline and 1-year activity predicts 1- and 2-year function, respectively) adjusted for demographics (age, gender, race/ethnicity, education, marital status) and health factors (osteoarthritis severity, knee symptoms, knee pain, knee injury, body mass index, comorbidity, depression, smoking, alcohol use, other joint pain). Increasing physical activity levels had a significant graded relationship with functional performance. Adults in physical activity quartile groups, from least to most active, had average gait speed of 4.0, 4.2, 4.3, 4.5 feet/second respectively at baseline (p-value for trend <.001) and 4.1, 4.2, 4.3, 4.5 feet/second after one year (p-value for trend <.001); increasing trends remained significant after adjusting for covariates. Findings were similar within gender and age groups. These prospective data showed a consistent graded relationship between physical activity level and better performance in adults with knee osteoarthritis. These findings support guidelines that encourage persons with arthritis who cannot attain minimum recommended physical activity to be as active as possible.
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影响因子：
3.5
作者：
McGrory, BJ;Harris, WH
通讯作者：
Harris, WH
影响因子：
--
作者：
Hootman, JM;Helmick, CG
通讯作者：
Helmick, CG
DOI：
10.1111/j.1532-5415.2005.53003.x
发表时间：
2005-01-01
影响因子：
6.3
作者：
de Vreede, PL;Samson, MM;Verhaar, HJJ
通讯作者：
Verhaar, HJJ
影响因子：
120.7
作者：
Church, Timothy S.;Earnest, Conrad P.;Blair, Steven N.
通讯作者：
Blair, Steven N.
影响因子：
19.6
作者：
Johansen, KL;Painter, P;Chertow, GM
通讯作者：
Chertow, GM