Evaluation of pleural lesions after pleurodesis with OK-432 by fluorodeoxyglucose-positron emission tomography/CT
Evaluation of pleural lesions after pleurodesis with OK-432 by fluorodeoxyglucose-positron emission tomography/CT
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氟脱氧葡萄糖-正电子发射断层扫描/CT评估OK-432胸膜固定术后胸膜病变
DOI：
10.1007/s12149-020-01508-0
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发表时间：
2020
影响因子：
2.6
通讯作者：
Yamagami Takuji
中科院分区：
文献类型：
--
作者：
Nishimori Miki;Yoshimatsu Rika;Iwasa Hitomi;Miyatake Kana;Nitta Noriko;Anayama Takashi;Yamagami Takuji
本研究的目的是确定FDG-PET/CT胸膜固定术后OK-432的变化，并探讨非恶性和恶性lesions.MethodsStudy参与者的变化之间的差异17例恶性胸部疾病的病史进行FDG-PET/CT胸膜固定术后使用OK-432，其中胸膜病变被确定为非恶性（n= 8）或恶性（n= 9）。计算所有胸膜病变的FDG摄取（SUVmax）。CT表现结果非恶性组（3/8）和恶性组（9/9）胸膜FDG摄取增加的患者数量差异有统计学意义FDG摄取增加的非恶性病变的平均SUVmax为2.3 ± 0.7，恶性病变为6.2 ± 2.2，两者之间有显著性差异（P< 0.01）。非恶性组病变的平均CT衰减为36 ± 11 HU，恶性组为34 ± 14 HU，差异不显著（p= 0.91）。结节状和线状形态在良、恶性病变中差异有显著性（P< 0.01）。所有非恶性病变均为linear.ConclusionsPositive FDG摄取显示在非恶性胸膜病变，以及在恶性胸膜病变胸膜固定术后使用OK-432。FDG聚集与CT形态学联合分析有助于良恶性病变的鉴别。
ObjectiveThis study aimed to determine changes in FDG-PET/CT after pleurodesis with OK-432 and to investigate differences in the changes between non-malignant and malignant lesions.MethodsStudy participants were 17 patients with a history of malignant chest disease who underwent FDG-PET/CT after pleurodesis using OK-432 and in whom pleural lesions were determined to be non-malignant (n= 8) or malignant (n= 9). FDG uptake (SUVmax) was counted on all pleural lesions. CT findings (CT attenuation, shape) of pleural lesions with increased FDG uptake were evaluated.ResultsThe number of patients with increased FDG uptake in the pleura differed significantly between the non-malignant group (3/8) and malignant group (9/9) (p< 0.01) The mean SUVmaxof non-malignant lesions with increased FDG uptake was 2.3 ± 0.7 vs. 6.2 ± 2.2 in malignant lesions, for a significant difference (p< 0.01). The mean CT attenuation of lesions was 36 ± 11 HU in the non-malignant group and 34 ± 14 HU in the malignant group, a difference that was not significant (p= 0.91). There was a significant difference in nodular and linear shapes between non-malignant and malignant lesions (p< 0.01). All non-malignant lesions were linear.ConclusionsPositive FDG uptake was shown in non-malignant pleural lesions as well as in malignant pleural lesions after pleurodesis using OK-432. Combined analysis of FDG accumulation and CT morphology is helpful to distinguish between benign and malignant lesions.
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影响因子：
2.6
作者：
Narayanaswamy, S.;Kamath, S.;Williams, M.
通讯作者：
Williams, M.
影响因子：
2.5
作者：
Muta, Fumihiko;Takamori, Shinzo;Shirouzu, Kazuo
通讯作者：
Shirouzu, Kazuo
影响因子：
5.3
作者：
Yoshida, Kimihide;Sugiura, Takahiko;Saijo, Nagahiro
通讯作者：
Saijo, Nagahiro
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影响因子：
0.8
作者：
Peek, Hilke;van der Bruggen, Wouter;Limonard, Gijs
通讯作者：
Limonard, Gijs
滑石粉胸膜固定术后氟脱氧葡萄糖正电子发射断层扫描和 CT。
影响因子：
9.6
作者：
B. Kwek;S. Aquino;A. Fischman
通讯作者：
A. Fischman