Opportunistic infections and immune deficiency in homosexual men.
Opportunistic infections and immune deficiency in homosexual men.
复制标题
男同性恋者的机会性感染和免疫缺陷。
DOI:
--
复制
发表时间:
1982
影响因子:
39.2
通讯作者:
I. Spigland
中科院分区:
文献类型:
--
作者:
D. Mildvan;U. Mathur;R. Enlow;P. L. Romain;R. Winchester;C. Colp;H. Singman;B. Adelsberg;I. Spigland
A syndrome of opportunistic infections and acquired immune deficiency occurred among four previously healthy homosexual men. Fever, leukopenia, and diminished delayed hypersensitivity were accompanied by various degrees of proctitis, perianal ulcerations, and lymphadenopathy. The infectious agents included Pneumocystis carinii, Cryptococcus neoformans, Candida albicans, herpes simplex virus, and cytomegalovirus. The immune deficiency was characterized as a persistent and profound selective decrease in the function as well as number of T lymphocytes of the helper/inducer subset and a possible activation of the suppressor/cytotoxic subset. Three patients died despite aggressive anti-infective therapy.
DOI:
--
发表时间:
1981
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Carney,WP;Rubin,RH;Hoffman,RA;Hansen,WP;Healey,K;Hirsch,MS
通讯作者:
Hirsch,MS
DOI:
10.1056/nejm198104023041403
发表时间:
1981
期刊:
The New England journal of medicine
影响因子:
--
作者:
Reinherz,EL;Geha,R;Wohl,ME;Morimoto,C;Rosen,FS;Schlossman,SF
通讯作者:
Schlossman,SF
影响因子:
3.1
作者:
Mangan,DF;Lopatin,DE
通讯作者:
Lopatin,DE