After the revolution? Ethical and social challenges in 'personalized genomic medicine'.

After the revolution? Ethical and social challenges in 'personalized genomic medicine'.
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DOI:
10.2217/pme.12.37
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发表时间:
2012-06-01
影响因子:
2.3
通讯作者:
McGowan ML
McGowan ML
中科院分区:
医学4区
文献类型:
--
作者:
Juengst ET;Settersten RA Jr;Fishman JR;McGowan ML

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个性化基因组医学(PGM)是一个目标,目前联合了一系列生物医学倡议,并被其倡导者宣传为一种“新的医疗保健范例”。其预期的优点包括个性化诊断和风险预测、更有效的预防和健康促进以及患者赋权。除了克服实现PGM的科学和技术障碍外,支持者可能会对这些承诺进行不同的解释和排序,这对实现PGM作为一种医疗保健方法具有伦理和社会影响。我们考察了对PGM优点的相互竞争的愿景以及他们可以在该领域采取的方向,以期预测研究人员、医疗保健提供者和公众未来可能面临的政策选择。
Personalized genomic medicine (PGM) is a goal that currently unites a wide array of biomedical initiatives, and is promoted as a ‘new paradigm for healthcare’ by its champions. Its promissory virtues include individualized diagnosis and risk prediction, more effective prevention and health promotion, and patient empowerment. Beyond overcoming scientific and technological hurdles to realizing PGM, proponents may interpret and rank these promises differently, which carries ethical and social implications for the realization of PGM as an approach to healthcare. We examine competing visions of PGM’s virtues and the directions in which they could take the field, in order to anticipate policy choices that may lie ahead for researchers, healthcare providers and the public.
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