Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity.

Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity.
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DOI:
10.1186/rr37
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发表时间:
2001
影响因子:
5.8
通讯作者:
Blanc PD
Blanc PD
中科院分区:
医学2区
文献类型:
--
作者:
Eisner MD;Katz PP;Yelin EH;Shiboski SC;Blanc PD

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自20世纪70年代末以来,哮喘的发病率和死亡率显著增加。作为哮喘严重程度的重要标志,住院率仍然很高。在可以获得医疗保健的成年人中,我们前瞻性地研究了242名年龄在18-50岁之间的哮喘患者,他们是从北加州的过敏和肺部内科医生中随机抽取的,以确定随后住院的危险因素。39名受试者(16%)报告在18个月的随访期内因哮喘住院。在控制哮喘严重程度的多因素Logistic回归分析中,非白人(优势比[OR],3.1;95%可信区间[CI],1.1-8.8)和低收入(OR,每10,000美元减值1.1;95%可信区间(CI),0.9-1.3)与哮喘住院风险相关。校正人口学特征后,哮喘严重程度评分(OR,每5分3.4分;95%,CI 1.7-6.8)和最近哮喘住院(OR,8.3;95%,CI,2.1-33.4)也与更高的风险相关。依赖急诊科服务进行紧急哮喘护理也与更大的住院可能性相关(OR,3.2;95%CI,1.0-9.8)。在没有控制哮喘严重程度的多因素分析中,低收入与住院的相关性更强(OR,每10,000美元减少1.2;95%CI,1.02-1.4)。在可以获得医疗保健的成年哮喘患者中,非白人、低收入和更严重的哮喘与更高的住院风险相关。对高危哮喘患者进行有针对性的干预可能会降低哮喘的发病率和死亡率。
The morbidity and mortality from asthma have markedly increased since the late 1970s. The hospitalization rate, an important marker of asthma severity, remains substantial. In adults with health care access, we prospectively studied 242 with asthma, aged 18–50 years, recruited from a random sample of allergy and pulmonary physician practices in Northern California to identify risk factors for subsequent hospitalization. Thirty-nine subjects (16%) reported hospitalization for asthma during the 18-month follow-up period. On controlling for asthma severity in multiple logistic regression analysis, non-white race (odds ratio [OR], 3.1; 95% confidence interval [CI], 1.1–8.8) and lower income (OR, 1.1 per $10,000 decrement; 95% CI, 0.9–1.3) were associated with a higher risk of asthma hospitalization. The severity-of-asthma score (OR, 3.4 per 5 points; 95%, CI 1.7–6.8) and recent asthma hospitalization (OR, 8.3; 95%, CI, 2.1–33.4) were also related to higher risk, after adjusting for demographic characteristics. Reliance on emergency department services for urgent asthma care was also associated with a greater likelihood of hospitalization (OR, 3.2; 95% CI, 1.0–9.8). In multivariate analysis not controlling for asthma severity, low income was even more strongly related to hospitalization (OR, 1.2 per $10,000 decrement; 95% CI, 1.02–1.4). In adult asthmatics with access to health care, non-white race, low income, and greater asthma severity were associated with a higher risk of hospitalization. Targeted interventions applied to high-risk asthma patients may reduce asthma morbidity and mortality.
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发表时间: 1998-11-01
期刊: MEDICAL CARE
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