Dissociating Verbal and Nonverbal Conceptual Processing in the Human Brain
Dissociating Verbal and Nonverbal Conceptual Processing in the Human Brain
复制标题
分离人脑中的言语和非言语概念处理
DOI：
--
复制
发表时间：
2006
影响因子：
3.2
通讯作者：
C. Price
中科院分区：
文献类型：
--
作者：
G. Thierry;C. Price
功能性神经影像学强调了语言和非语言处理共享的左半球概念系统，尽管有神经心理学证据表明，识别语言和非语言刺激的能力在左半球和右半球病变的患者中可以双重分离。以前的尝试控制知觉差异之间的言语和非言语刺激的功能性神经影像学研究可能有隐藏的差异，在概念层面上产生的。在这里，我们使用了一种不同的方法，并通过寻找视觉和听觉模态共同的非模态言语和非言语概念激活来控制感知混淆。除了左半球的概念系统激活的所有有意义的刺激，我们观察到的左/右双分离的语言和非语言的概念处理，预测的神经心理学研究。左侧中颞区和上级颞区选择性地更多地参与对单词的理解，右侧中梭状回和右侧后中颞区选择性地更多地参与对环境声音和图像的理解。因此，言语/非言语概念加工分离的神经解剖学基础被建立。
Functional neuroimaging has highlighted a left-hemisphere conceptual system shared by verbal and nonverbal processing despite neuropsychological evidence that the ability to recognize verbal and nonverbal stimuli can doubly dissociate in patients with left- and right-hemisphere lesions, respectively. Previous attempts to control for perceptual differences between verbal and nonverbal stimuli in functional neuroimaging studies may have hidden differences arising at the conceptual level. Here we used a different approach and controlled for perceptual confounds by looking for amodal verbal and nonverbal conceptual activations that are common to both the visual and auditory modalities. In addition to the left-hemisphere conceptual system activated by all meaningful stimuli, we observed the left/right double dissociation in verbal and nonverbal conceptual processing, predicted by neuropsychological studies. Left middle and superior temporal regions were selectively more involved in comprehending wordsheard or readand the right midfusiform and right posterior middle temporal cortex were selectively more involved in making sense of environmental sounds and images. Thus, the neuroanatomical basis of a verbal/nonverbal conceptual processing dissociation is established.
DOI：
10.1073/pnas.94.26.14792
发表时间：
1997-12-23
影响因子：
11.1
作者：
Thompson-Schill, SL;D'Esposito, M;Farah, MJ
通讯作者：
Farah, MJ
DOI：
10.1073/pnas.97.22.11800
发表时间：
2000-10-24
影响因子：
11.1
作者：
Rauschecker, JP;Tian, B
通讯作者：
Tian, B