Movement‐ and task‐related activations of motor cortical areas: A positron emission tomographic study
Movement‐ and task‐related activations of motor cortical areas: A positron emission tomographic study
复制标题
运动皮质区域的运动和任务相关激活：正电子发射断层扫描研究
作者：
P. Remy;M. Zilbovicius;A. Leroy;A. Syrota;Y. Samson
用正电子发射断层扫描重复测量局部脑血流量的方法，研究了10名正常受试者在两种不同的手指运动任务，即所有手指重复屈伸和中指反复屈伸时所诱发的局部皮质激活。全指运动只激活了运动对侧的初级感觉运动皮质(SM)和辅助运动区(SMA)。然而，在这项运动任务中，SMA的激活显然与任务有关，因为只有在听觉提示触发运动时才能观察到它，而当它是自我调节的时候就看不到了。中指的移动是在自定节奏的条件下进行的。它诱导了比全指运动复杂得多的激活模式，其特征是运动侧的SM和SMA高度激活，以及这些区域轻微的同侧激活。我们认为，这种皮质激活模式可能反映了手指运动的个体化过程，或者反映了这种不寻常的、技术上困难的运动的早期运动学习阶段。我们的数据还证实，SM的激活与运动的内在参数密切相关，而SMA可能由运动实现和准备的不同方面激活。
Using repeated measurements of regional cerebral blood flow with positron emission tomography, we investigated the regional cortical activations induced in 10 normal subjects, by two different finger motor tasks, i.e., a repeated flexion–extension of all fingers and a repeated flexion–extension of the middle finger. The all‐finger movement only activated the primary sensorimotor cortex (SM) and the supplementary motor area (SMA) contralateral to the movement. However, the activation of the SMA was clearly task related during this motor task, because it was only observed when the movement was triggered by an auditory cue but not when it was self‐paced. The middle finger movement was performed during self‐paced conditions. It induced a much more complex pattern of activation than the all‐finger movement, characterized by a high degree of SM and SMA activation contralateral to the side of the movement, as well as a slight ipsilateral activation of these areas. We suggest that this pattern of cortical activation may reflect the process of individuating finger movement or the early stages of motor learning of this unusual and technically difficult movement. Our data also confirm that the SM activation is closely linked to the intrinsic parameters of the movement; while the SMA may be activated by different aspects of the movement realization and preparation.
影响因子：
15.9
作者：
Schieber,MH
通讯作者：
Schieber,MH
影响因子：
3.7
作者：
RAICHLE, ME;FIEZ, JA;PETERSEN, SE
通讯作者：
PETERSEN, SE
DOI：
10.1073/pnas.87.1.256
发表时间：
1990-01-01
影响因子：
11.1
作者：
PARDO, JV;PARDO, PJ;RAICHLE, ME
通讯作者：
RAICHLE, ME