Comparing the dynamic course of heroin, cocaine, and methamphetamine use over 10 years.

Comparing the dynamic course of heroin, cocaine, and methamphetamine use over 10 years.
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DOI:
10.1016/j.addbeh.2008.07.024
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发表时间:
2008-12
影响因子:
4.4
通讯作者:
Li, Libo
Li, Libo
中科院分区:
医学2区
文献类型:
--
作者:
Hser, Yih-Ing;Evans, Elizabeth;Huang, David;Brecht, Mary-Lynn;Li, Libo

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为了研究药物使用轨迹随时间的动态变化,我们分析了1797名海洛因、可卡因和甲基苯丙胺(冰毒)使用者在开始使用药物后10年内的发作类型和戒烟预测因素。大多数事件反映了高使用和监禁,但这些事件更频繁地发生在海洛因和冰毒使用者中。冰毒(RR 2.57,1.79-3.70; 2.57,1.80-3.67)和可卡因(RR 2.00,1.42-2.81; 2.10,1.63-2.72)使用者的当前治疗和自助参与以及冰毒使用者的戒烟史(RR 1.11,1.06-1.17)预测了戒烟。在法律的监督下的所有吸毒者(RR 0.55-0.69)以及吸毒早期的海洛因(RR 0.66,0.45-0.97)和冰毒吸毒者(RR 0.73,0.60-0.89)中,戒烟的可能性较小。相对于可卡因或甲基苯丙胺的使用,海洛因使用的特点是持续大量使用,通常只有通过监禁才能中断。虽然治疗和/或自助参与可以促进戒毒,但很少有人在首次使用后的10年内有这些经历。
To examine dynamic changes in drug-use trajectories over time we analyzed episode types and predictors of quitting use over the 10 years following drug-use initiation for 1797 heroin, cocaine, and methamphetamine (meth) users. Most episodes reflected high use and incarceration, however these events occurred more frequently among heroin and meth users. Quitting was predicted by current treatment and self-help participation among meth (RR 2.57, 1.79–3.70; 2.57, 1.80–3.67) and cocaine (RR 2.00, 1.42–2.81; 2.10, 1.63–2.72) users, and by a history of quitting for meth users (RR 1.11, 1.06–1.17). Quitting was less likely among all users under legal supervision (RR 0.55–0.69) and among heroin (RR 0.66, 0.45–0.97) and meth users (RR 0.73, 0.60–0.89) with an early drug-use onset. Relative to cocaine or meth use, heroin use was characterized by persistent use at a high-level which was often only interrupted by incarceration. While quitting drug use can be facilitated by treatment and/or self-help participation, few people had these experiences in the 10 years following first use.
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