Dendritic cells: novel players in fibrosis and scleroderma.
Dendritic cells: novel players in fibrosis and scleroderma.
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DOI:
10.1007/s11926-011-0215-5
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发表时间:
2012-02
影响因子:
5
通讯作者:
Lu TT
中科院分区:
文献类型:
--
作者:
Lu TT
Dendritic cells are professional antigen-presenting cells that are most studied for their function in mediating T-cell tolerance and T-cell activation. In addition, recent evidence indicates that dendritic cells can regulate the vasculature and function of fibroblast-type cells. The potential contribution of dendritic cells to scleroderma and fibrosis is not well-understood. In this article, we review recent studies as well as describe our own ongoing work that points toward a role for dendritic cells in scleroderma and fibrosis.
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影响因子:
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