Properties of Calcium Phosphate Cements With Different Tetracalcium Phosphate and Dicalcium Phosphate Anhydrous Molar Ratios.
Properties of Calcium Phosphate Cements With Different Tetracalcium Phosphate and Dicalcium Phosphate Anhydrous Molar Ratios.
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DOI：
10.6028/jres.113.025
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发表时间：
2008-11
影响因子：
1.5
通讯作者：
Chow LC
中科院分区：
文献类型：
--
作者：
Hirayama S;Takagi S;Markovic M;Chow LC
以磷酸四钙（TTCP）和无水磷酸二钙（DCPA）为原料，以1/1，1/2和1/3的摩尔比，以粉末和水为液体，制备磷酸钙骨水泥（CPC）。将试样在类生理溶液（PLS）中浸泡1 d、5 d和10 d后，测定试样的径向抗拉强度、孔隙率和相组成（粉末X射线衍射）。使用双恒定组成法测量酸化PLS中的骨水泥溶解速率。所有骨水泥的凝固时间相同（（30 ± 1）min）。随着TTCP/DCPA比率的降低，并且在某些情况下，也随着PLS浸泡时间的降低而降低。孔隙率和羟基磷灰石（HA）的形成与PLS浸泡时间增加。TTCP/DCPA比例为1/2和1/3的水泥形成缺钙HA，比比例为1/1的水泥溶解更快。总之，可以用一系列TTCP/DCPA比率制备骨水泥，比率较低的骨水泥强度较低，但在酸化PLS中溶解更快。
Calcium phosphate cements (CPCs) were prepared using mixtures of tetracalcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA), with TTCP/DCPA molar ratios of 1/1, 1/2, or 1/3, with the powder and water as the liquid. Diametral tensile strength (DTS), porosity, and phase composition (powder x-ray diffraction) were determined after the set specimens have been immersed in a physiological-like solution (PLS) for 1 d, 5 d, and 10 d. Cement dissolution rates in an acidified PLS were measured using a dual constant composition method. Setting times ((30 ± 1) min) were the same for all cements. DTS decreased with decreasing TTCP/DCPA ratio and, in some cases, also decreased with PLS immersion time. Porosity and hydroxyapatite (HA) formation increased with PLS immersion time. Cements with TTCP/DCPA ratios of 1/2 and 1/3, which formed calcium-deficient HA, dissolved more rapidly than the cement with a ratio of 1/1. In conclusion, cements may be prepared with a range of TTCP/DCPA ratios, and those with lower ratio had lower strengths but dissolved more rapidly in acidified PLS.
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影响因子：
5
作者：
ISHIKAWA, K;TAKAGI, S;ASAOKA, K
通讯作者：
ASAOKA, K
DOI：
10.1002/jbm.b.10009
发表时间：
2003-05-15
影响因子：
3.4
作者：
Chow, LC;Markovic, M;Takagi, S
通讯作者：
Takagi, S
影响因子：
4.2
作者：
EIDELMAN, N;CHOW, LC;BROWN, WE
通讯作者：
BROWN, WE
影响因子：
7.6
作者：
FUKASE, Y;EANES, ED;BROWN, WE
通讯作者：
BROWN, WE
DOI：
10.1002/jbm.820291210
发表时间：
1995-12-01
期刊：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
影响因子：
--
作者：
ISHIKAWA, K;ASAOKA, K
通讯作者：
ASAOKA, K