How do auditory verbal hallucinations in patients differ from those in non-patients?

How do auditory verbal hallucinations in patients differ from those in non-patients?
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DOI:
10.3389/fnhum.2012.00025
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发表时间:
2012
影响因子:
2.9
通讯作者:
Larøi F
Larøi F
中科院分区:
医学3区
文献类型:
--
作者:
Larøi F

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听性言语幻觉(AVH)是有各种临床诊断的个体所经历的,例如精神病,但普通人群中的相当少数的健康个体也可能经历这种情况。虽然在过去的几十年里已经进行了大量的研究,但对AVH产生的机制和因素仍然知之甚少。澄清这一问题的一种方法是比较患者和非患者人群中的AVH。特别是,这些群体之间的差异将提供有关AVH出现的重要信息。在对连续体假说的概念进行一般性介绍和讨论之后,将回顾比较经历动静脉曲张的患者和非患者的研究。这将包括除了神经成像和认知研究外,还将包括研究动静脉动静脉高压的现象学特征。虽然我们开始在现象学水平上阐明这两种类型的动静脉动静脉高压之间的重要差异,但很少有研究直接比较患者和非患者动静脉动静脉高压在潜在的大脑相关性和认知机制方面的差异。然而,基于最近对现象学差异的研究,有两个问题需要解决,即患者中AVH的高度负面情绪内容和非患者人群中AVH的早期发病。将讨论对未来研究的建议。
Auditory verbal hallucinations (AVHs) are experienced by individuals with various clinical diagnoses, such as psychosis, but also a significant minority of healthy individuals from the general population may experience them. Although much research has been carried out the past few decades, the mechanisms and factors underlying the emergence of AVHs is still poorly understood. One way of clarifying this issue involves comparing AVHs in patient and non-patient populations. In particular, differences between these groups will provide important information concerning the emergence of AVHs. After a general presentation and discussion of the notion of a continuum hypothesis, studies comparing patients with non-patients experiencing AVHs will be reviewed. This will comprise studies examining the phenomenological characteristics of AVHs in addition to neuroimaging and cognitive studies. Although we are beginning to elucidate important differences on a phenomenological level between these two types of AVHs, far too few studies have directly compared patient and non-patient AVHs in terms of underlying cerebral correlates and cognitive mechanisms. Nevertheless, and based on recent research on phenomenological differences, two issues stand out that need to be addressed, namely, the highly negative emotional content of AVHs in patients and the early onset of AVHs in non-patients populations. Suggestions for future research will be discussed.
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