The relation of the X-ray B-factor to protein dynamics: insights from recent dynamic solid-state NMR data
The relation of the X-ray B-factor to protein dynamics: insights from recent dynamic solid-state NMR data
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X 射线 B 因子与蛋白质动力学的关系:来自最新动态固态 NMR 数据的见解
DOI:
10.1080/07391102.2012.689695
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发表时间:
2012
影响因子:
4.4
通讯作者:
Krushelnitsky
中科院分区:
文献类型:
--
作者:
Reichert;Zinkevich;Saalwachter;Krushelnitsky
In addressing the potential use of B-factors derived from X-ray scattering data of proteins for the understanding the (functional) dynamics of proteins, we present a comparison of B-factors of five different proteins (SH3 domain, Crh, GB1, ubiquitin and thioredoxin) with data from recent solid-state nuclear magnetic resonance experiments reflecting true (rotational) dynamics on well-defined timescales. Apart from trivial correlations involving mobile loop regions and chain termini, we find no significant correlation of B-factors with the dynamic data on any of the investigated timescales, concluding that there is no unique and general correlation of B-factors with the internal reorientational dynamics of proteins.
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影响因子:
15
作者:
Lewandowski, Jozef R.;Sein, Julien;Emsley, Lyndon
通讯作者:
Emsley, Lyndon
DOI:
10.1073/pnas.88.7.2773
发表时间:
1991-04-01
影响因子:
11.1
作者:
KURIYAN, J;WEIS, WI
通讯作者:
WEIS, WI
DOI:
10.1002/pro.335
发表时间:
2010
期刊:
Protein science : a publication of the Protein Society
影响因子:
--
作者:
Jensen,DavinR;Woytovich,Christopher;Li,Margie;Duvnjak,Petar;Cassidy,MichaelS;Frederick,RonnieO;Bergeman,LaiF;Peterson,FrancisC;Volkman,BrianF
通讯作者:
Volkman,BrianF
影响因子:
5.6
作者:
Charpentier TH;Thompson LE;Liriano MA;Varney KM;Wilder PT;Pozharski E;Toth EA;Weber DJ
通讯作者:
Weber DJ
影响因子:
15
作者:
Giraud, N;Böckmann, A;Emsley, L
通讯作者:
Emsley, L