The BAFFling persistence of memory B cells.

The BAFFling persistence of memory B cells.
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DOI:
10.1084/jem.20202057
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发表时间:
2021-02-01
期刊:
The Journal of experimental medicine
影响因子:
--
通讯作者:
Zikherman J
Zikherman J
中科院分区:
其他
文献类型:
--
作者:
Brooks JF;Zikherman J

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The pathways involved in the persistence of memory B cells are largely unknown. In this issue, two groups (Müller-Winkler et al. and Lau et al.) take complementary approaches to identify an essential role for BAFFR in the survival of memory B cells. Although BAFF/BLyS and its receptor, BAFFR, play critical roles in naive B cell survival, the pathways involved in the persistence of memory B cells are largely unknown. In this issue of JEM, two groups, Müller-Winkler et al. (https://doi.org/10.1084/jem.20191393) and Lau et al. (https://doi.org/10.1084/jem.20191167), take complementary approaches to identify an essential role for BAFFR in the survival of memory B cells.
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