Changes in the somatotopic organization of the cat lumbar spinal cord following peripheral nerve transection and regeneration
Changes in the somatotopic organization of the cat lumbar spinal cord following peripheral nerve transection and regeneration
复制标题
周围神经横断和再生后猫腰脊髓体位组织的变化
DOI：
10.1016/0006-8993(83)91064-8
复制
发表时间：
1983
期刊：
影响因子：
2.9
通讯作者：
S. Lisney
中科院分区：
文献类型：
--
作者：
S. Lisney
用玻璃微电极记录正常猫和切断左侧坐骨神经和隐神经1个月或9个月后的猫脊髓L6节段左侧背角神经元的活动。在正常动物的感受野的L6背角神经元兴奋的触觉刺激的腿somatotopically组织，在内侧和中央背角的神经元有感受野的远端部分的腿，特别是脚趾，和神经元在外侧背角有感受野的近端部分的腿，臀部和下背部。这种躯体映射以前已经被展示过了。一个月后，神经节没有细胞响应触觉刺激的远端腿和细胞的内侧和中央部分的背角现在有感受野的近端腿，背部和背部。这些新的感受野似乎没有任何躯体位置组织。外侧背角神经元感受野正常。9个月后，神经节神经元的内侧和中央部分的腰背角的接受野的远端腿，但他们表现出一些异常的功能，并没有证据表明，在正常动物的躯体组织的回报。外侧背角细胞仍有正常的感受野。
Glass microelectrodes were used to record the activity of neurones in the left dorsal horn of the L6 segment of the spinal cord of normal cats and cats in which the left sciatic and saphenous nerves had been cut 1 or 9 months previously. In the normal animals the receptive fields of L6 dorsal horn neurones excited by tactile stimulation of the leg were somatotopically organized, with neurones in the medial and central dorsal horn having receptive fields on the distal parts of the leg, particularly the toes, and neurones in the lateral dorsal horn having receptive fields on the proximal parts of the leg, buttock and lower back. This somatotopy has been shown before. One month after nerve section no cells responded to tactile stimulation of the distal leg and cells in the medial and central parts of the dorsal horn now had receptive fields on the proximal leg, buttock and back. There did not appear to be any somatotopic organization of these new receptive fields. Lateral dorsal horn neurones had normal receptive fields. Nine months after nerve section neurones in the medial and central parts of the lumbar dorsal horn had receptive fields on the distal leg but they showed several abnormal features and there was no evidence of a return of the somatotopic organization seen in normal animals. Lateral dorsal horn cells still had normal receptive fields.
DOI：
10.1113/jphysiol.1981.sp013664
发表时间：
1981-04
期刊：
The Journal of Physiology
影响因子：
--
作者：
K. Horch;S. Lisney
通讯作者：
K. Horch;S. Lisney