Heterogeneity in bio¢lms
Heterogeneity in bio¢lms
复制标题
生物膜的异质性
DOI：
--
复制
发表时间：
2000
期刊：
影响因子：
--
通讯作者：
U. Szewzyk
中科院分区：
文献类型：
--
作者：
J. Wimpenny;W. Manz;U. Szewzyk
生物膜，微生物在界面上的积累，已经描述了每一个支持生命的水系统。这些微生物群落的结构范围从分散的单细胞单层到宏观尺寸的厚的粘液结构（微生物垫;藻类-微生物协会;滴滤生物膜）。近年来，来自许多不同环境的生物膜的结构已经通过使用各种各样的显微镜、物理化学和分子生物学技术被记录和评估，揭示了通常复杂的3D结构。与此同时，越来越多的复杂数学模型和模拟被开发出来，以解释生物膜的发展，结构和相互作用。决定生物膜空间结构的力，包括小菌落、细胞外聚合物（EPS）和通道，仍然是有争议的主题。为了对生物膜中观察到的结构做出结论性的解释，需要调查、建模和实验研究这两个领域的合作。不断扩大的分子技术领域不仅允许越来越详细的文件的空间分布的物种，但也功能活动的单细胞在其生物膜环境。这些新方法必将揭示生物膜形成和行为的发育过程中所涉及的机制。fl 2000欧洲微生物学会联合会。由Elsevier Science B. V.出版，版权所有。
Biofilms, accumulations of microorganisms at interfaces, have been described for every aqueous system supporting life. The structure of these microbial communities ranges from monolayers of scattered single cells to thick, mucous structures of macroscopic dimensions (microbial mats; algal-microbial associations ; trickling filter biofilms). During recent years the structure of biofilms from many different environments has been documented and evaluated by use of a broad variety of microscopic, physico-chemical and molecular biological techniques, revealing a generally complex 3D structure. Parallel to these investigations more and more complex mathematical models and simulations were developed to explain the development, structures, and interactions of biofilms. The forces determining the spatial structure of biofilms, including microcolonies, extracellular polymeric substances (EPS), and channels, are still the subject of controversy. To achieve conclusive explanations for the structures observed in biofilms the cooperation of both fields of investigation, modelling and experimental research, is necessary. The expanding field of molecular techniques not only allows more and more detailed documentation of the spatial distribution of species, but also of functional activities of single cells in their biofilm environment. These new methods will certainly reveal new insights in the mechanisms involved in the developmental processes involved in the formation and behavior of biofilms. fl 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
影响因子：
56.9
作者：
Davies, DG;Parsek, MR;Greenberg, EP
通讯作者：
Greenberg, EP