Robotic versus open extended cholecystectomy for T1a-T3 gallbladder cancer: A matched comparison.
Robotic versus open extended cholecystectomy for T1a-T3 gallbladder cancer: A matched comparison.
复制标题
机器人与开放式扩大胆囊切除术治疗 T1a ～ T3 胆囊癌：匹配比较
DOI：
10.3389/fsurg.2022.1039828
复制
发表时间：
2022
影响因子：
1.8
通讯作者：
Wu, Linquan
中科院分区：
文献类型：
--
作者：
Yang, Jun;Li, Enliang;Wang, Cong;Luo, Shuaiwu;Fu, Zixuan;Peng, Jiandong;Liao, Wenjun;Wu, Linquan
关键词：
机器人胆囊切除术（REC）的可行性和安全性仍不确定。本研究旨在比较REC与开放性扩大胆囊切除术（OEC）治疗T1 a-T3胆囊癌的短期和长期结局。2015年1月至2022年4月，28例患者在我中心接受了REC。为了尽量减少任何混杂因素，根据患者的人口统计学、肝功能指标、T分期和症状进行1：2倾向评分匹配分析。对人口统计学、围手术期结局和长期肿瘤学结局的数据进行了审查。术后即刻REC组的视觉模拟量表评分明显低于OEC组（3.68 ± 2.09 vs. 4.73 ± 1.85，P = 0.008），术后第1天（2.96 ± 1.75 vs. 3.69 ± 1.41，P = 0.023），术后第2天（2.36 ± 1.55 vs. 2.92 ± 1.21，P = 0.031）。此外，REC组的首次Amplitude时间更短（P = 0.043），引流管拔除时间更短（P = 0.038），术后住院时间更短（P = 0.037），但REC组的住院费用明显更高（P < 0.001）。然而，REC组和OEC组的手术时间（P = 0.134）、术中失血量（P = 0.467）或术后发病率（P = 0.227）或死亡率（P = 0.289）无统计学显著差异。在长期结局方面，OEC组和REC组的3年无病生存率相当（43.1% vs. 57.2%，P = 0.684），3年总生存率也相当（62.8% vs. 75.0%，P = 0.619）。对于选定的T1 a-T3胆囊癌患者，REC可能是OEC的有效和安全的替代方案，无论是短期还是长期结局。
The feasibility and safety of robotic extended cholecystectomy (REC) are still uncertain. This study was performed to compare the short- and long-term outcomes of REC with those of open extended cholecystectomy (OEC) for T1a–T3 gallbladder cancer. From January 2015 to April 2022, 28 patients underwent REC in our center. To minimize any confounding factors, a 1:2 propensity score-matching analysis was conducted based on the patients’ demographics, liver function indicators, T stage, and symptoms. The data regarding demographics, perioperative outcomes, and long-term oncologic outcomes were reviewed. The visual analogue scale score was significantly lower in the REC than OEC group immediately postoperatively (3.68 ± 2.09 vs. 4.73 ± 1.85, P = 0.008), on postoperative day 1 (2.96 ± 1.75 vs. 3.69 ± 1.41, P = 0.023), and on postoperative day 2 (2.36 ± 1.55 vs. 2.92 ± 1.21, P = 0.031). In addition, the REC group exhibited a shorter time to first ambulation (P = 0.043), a shorter time to drainage tube removal (P = 0.038), and a shorter postoperative stay (P = 0.037), but hospital costs were significantly higher in the REC group (P < 0.001). However, no statistically significant difference was found in the operation time (P = 0.134), intraoperative blood loss (P = 0.467), or incidence of postoperative morbidity (P = 0.227) or mortality (P = 0.289) between the REC and OEC groups. In regard to long-term outcomes, the 3-year disease-free survival rate was comparable between the OEC and REC groups (43.1% vs. 57.2%, P = 0.684), as was the 3-year overall survival rate (62.8% vs. 75.0%, P = 0.619). REC can be an effective and safe alternative to OEC for selected patients with T1a–T3 gallbladder cancer with respect to short- and long-term outcomes.
登录
查看更多内容
影响因子：
3.7
作者：
Khan S;Beard RE;Kingham PT;Fong Y;Boerner T;Martinie JB;Vrochides D;Buell JF;Berber E;Kahramangil B;Troisi RI;Vanlander A;Molinari M;Tsung A
通讯作者：
Tsung A
影响因子：
5.9
作者：
Bae, Jae Seok;Kim, Se Hyung;Han, Joon Koo
通讯作者：
Han, Joon Koo
影响因子：
3.7
作者：
Chen, Po-Da;Wu, Chao-Ying;Wu, Yao-Ming
通讯作者：
Wu, Yao-Ming
DOI：
10.1007/s00464-012-2330-4
发表时间：
2012-11-01
影响因子：
3.1
作者：
Shen, Bai-Yong;Zhan, Qian;Li, Hong-Wei
通讯作者：
Li, Hong-Wei
影响因子：
9
作者：
Sasaki, Eiji;Nagino, Masato;Nimura, Yuji
通讯作者：
Nimura, Yuji