The neuroleptic malignant syndrome: agent and host interaction

The neuroleptic malignant syndrome: agent and host interaction
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抗精神病药物恶性综合征:药物与宿主的相互作用

DOI:
10.1111/j.1600-0447.1986.tb02694.x
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发表时间:
1986
影响因子:
6.7
通讯作者:
H. Munitz
H. Munitz
中科院分区:
医学1区
文献类型:
--
作者:
A. Shalev;H. Munitz

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摘要本综述包括对120例抗精神病药恶性综合征(NMS)病例报告的详尽分析,这些病例报告代表了关于该综合征的大多数已发表的临床数据。流行病学,临床和生物学参数,以及那些有关的代理和综合征的治疗,严格评价的基础上,这些数据。抗精神病药物负荷率在NMS的发展中起着重要作用。考虑NMS后需要抗精神病治疗的患者的再激发和善后。
ABSTRACT This review comprises an exhaustive analysis of 120 case reports of neuroleptic malignant syndrome (NMS) representing the majority of published clinical data on this syndrome. Epidemiological, clinical and biological parameters, as well as those concerning the agent and the treatment of the syndrome, are critically evaluated on the basis of this data. The rate of neuroleptic loading is shown to play a cardinal role in the development of NMS. Rechallenge and aftercare of patients who need anti‐psychotic treatment after NMS are considered.
高效和低效抗精神病药的剂量不同。
DOI: 10.1176/ajp.141.6.748
发表时间: 1984
期刊: The American journal of psychiatry
影响因子: --
作者:
Baldessarini,RJ;Katz,B;Cotton,P
通讯作者: Cotton,P