Agent-based simulations of complex droplet pattern formation in a two-branch microfluidic network.
Agent-based simulations of complex droplet pattern formation in a two-branch microfluidic network.
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DOI：
10.1039/b916380h
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发表时间：
2010-02-07
期刊：
影响因子：
6.1
通讯作者：
Gaver DP 3rd
中科院分区：
文献类型：
--
作者：
Smith BJ;Gaver DP 3rd
我们开发了一种基于代理的计算模拟，以调查所表现出的复杂行为，通过一个简单的两个分支的微流体网络，其中一个通道分裂成两个不对称的分支，重新连接下游的不混溶液滴的初始定期间隔列车。正如Fuerstman等人（M. J. Fuerstman，P. Garbenki和G. M. Whitesides，Science，2007，315，828-832），由液滴引起的每个段内的流速的变化导致在出口中出现复杂的液滴间隔图案，导致周期性和非周期性行为。我们的模型采用了一种高效的基于代理的建模方法，在网络的每一部分的流量是使用粘性和界面流的基本概念来确定。模拟跨越物理参数空间，包括液滴间距，表面张力，粘度和几何形状的变化。这些模拟表明定性协议与Fuerstman等人的研究结果，包括穿插的周期性和非周期性域的预测。我们预测，降低液滴对整体压降的贡献（减小管半径或表面张力，增加粘度）将导致复杂性增加。系统的几何构型对图案的形成也很关键;分支长度的较大差异通常导致流出通道中的高阶周期性。非周期性的结果表明，从这个纯粹的确定性系统所产生的混沌行为的可能性。将流体力学的基本原理与基于代理的仿真技术相结合，可以为更复杂系统的设计和分析提供一种高效的手段。
We develop an agent-based computational simulation to investigate the complex behavior exhibited by an initially regularly spaced train of immiscible droplets passing through a simple two-branch microfluidic network wherein a channel splits into two asymmetric branches that reconnect downstream. As observed by Fuerstman et al. (M. J. Fuerstman, P. Garstecki and G. M. Whitesides, Science, 2007, 315, 828–832), variations in the flow rates within each segment induced by the droplets cause complex droplet spacing patterns to occur in the outlet, leading to periodic and aperiodic behavior. Our model utilizes a highly efficient agent-based modeling approach, where the flow-rates in each section of the network are determined using fundamental concepts of viscous and interfacial flows. Simulations spanned physical parameter space that includes variation in droplet spacing, surface tension, viscosity, and geometry. These simulations demonstrate qualitative agreement with the findings of Fuerstman et al, including the prediction of interspersed periodic and aperiodic domains. We predict that decreasing droplet contribution to the overall pressure drop (reducing the tube radius or surface tension, increasing the viscosity) would result in increased complexity. The geometric configuration of the system is also critical to pattern formation; a greater disparity in branch length generally results in higher-order periodicities in the outflow channel. The aperiodic results indicate the likelihood of chaotic behavior arising from this purely deterministic system. The consideration of fundamental fluid mechanical principles coupled to the agent-based simulation technique may provide a highly efficient means for the design and analysis of more complex systems.
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影响因子：
2.3
作者：
Adzima, Brian J.;Velankar, Sachin S.
通讯作者：
Velankar, Sachin S.
DOI：
10.1063/1.857530
发表时间：
1989-10-01
期刊：
PHYSICS OF FLUIDS A-FLUID DYNAMICS
影响因子：
--
作者：
RATULOWSKI, J;CHANG, HC
通讯作者：
CHANG, HC
影响因子：
56.9
作者：
Fuerstman, Michael J.;Garstecki, Piotr;Whitesides, George M.
通讯作者：
Whitesides, George M.
影响因子：
2.4
作者：
Jousse, Fabien;Farr, Robert;Garstecki, Piotr
通讯作者：
Garstecki, Piotr
影响因子：
8.6
作者：
Schindler, Michael;Ajdari, Armand
通讯作者：
Ajdari, Armand