Two temporal channels in human V1 identified using fMRI.

Two temporal channels in human V1 identified using fMRI.
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DOI:
10.1016/j.neuroimage.2009.03.078
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发表时间:
2009-08-01
期刊:
影响因子:
5.7
通讯作者:
Wandell BA
Wandell BA
中科院分区:
医学1区
文献类型:
--
作者:
Horiguchi H;Nakadomari S;Misaki M;Wandell BA

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人类对相当广泛的动态刺激的视觉敏感性可以使用两个时间通道精确地建模。在这里,我们分析了fMRI对空间均匀刺激的时间阶跃反应的测量结果,以估计人类初级视觉皮层(V1)中的这些通道。与心理物理学文献一致,V1功能磁共振成像的时间反应被准确地建模为两个(瞬态和持续)通道的混合。我们估计了这两个通道在一定偏心率范围内的相对贡献。我们发现V1的所有部分都包含一个显著的瞬态响应。中央视野表征包括显著的持续响应,但持续通道信号的振幅随偏心率下降。持续的信号可能反映了中央视野对模式识别和颜色的重视;视觉周边的主导瞬态反应可能反映了人类视觉注意系统的反应。
Human visual sensitivity to a fairly broad class of dynamic stimuli can be modeled accurately using two temporal channels. Here, we analyze fMRI measurements of the temporal step response to spatially uniform stimuli to estimate these channels in human primary visual cortex (V1). In agreement with the psychophysical literature, the V1 fMRI temporal responses are modeled accurately as a mixture of two (transient and sustained) channels. We derive estimates of the relative contributions from these two channels at a range of eccentricities. We find that all portions of V1 contain a significant transient response. The central visual field representation includes a significant sustained response, but the amplitude of the sustained channel signal declines with eccentricity. The sustained signals may reflect the emphasis on pattern recognition and color in the central visual field; the dominant transient response in the visual periphery may reflect responses in the human visual attention system.
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