Characterization of an entomopathogenic fungi target integument protein, Bombyx mori single domain von Willebrand factor type C, in the silkworm, Bombyx mori
Characterization of an entomopathogenic fungi target integument protein, Bombyx mori single domain von Willebrand factor type C, in the silkworm, Bombyx mori
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家蚕中昆虫病原真菌靶外皮蛋白 Bombyx mori 单域 von Willebrand 因子 C 型的表征
DOI:
10.1111/imb.12293
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发表时间:
2017-06
影响因子:
2.6
通讯作者:
Erjun Ling
中科院分区:
文献类型:
--
作者:
Fang Han;Anrui Lu;Yi Yuan;Wuren Huang;Brenda T. Beerntsen;Junyi Huang;Erjun Ling
The insect cuticle works as the first line of defence to protect insects from pathogenic infections and water evaporation. However, the old cuticle must be shed in order to enter the next developmental stage. During each ecdysis, moulting fluids are produced and secreted into the area among the old and new cuticles. In a previous study, the protein Bombyx mori single domain von Willebrand factor type C (BmSVWC; BGIBMGA011399) was identified in the moulting fluids of Bo. mori and demonstrated to regulate ecdysis. In this study we show that in Bo. mori larvae, BmSVWC primarily locates to the integument (epidermal cells and cuticle), wing discs and head. During the moulting stage, BmSVWC is released into the moulting fluids, and is then produced again by epidermal cells after ecdysis. Fungal infection was shown to decrease the amount of BmSVWC in the cuticle, which indicates that BmSVWC is a target protein of entomopathogenic fungi. Thus, BmSVWC is mainly involved in maintaining the integrity of the integument structure, which serves to protect insects from physical damage and pathogenic infection.
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影响因子:
4.8
作者:
Shao, Qimiao;Yang, Bing;Ling, Erjun
通讯作者:
Ling, Erjun
DOI:
10.1093/bioinformatics/8.3.275
发表时间:
1992-06-01
期刊:
COMPUTER APPLICATIONS IN THE BIOSCIENCES
影响因子:
--
作者:
JONES, DT;TAYLOR, WR;THORNTON, JM
通讯作者:
THORNTON, JM
影响因子:
4.4
作者:
Xiong GH;Xing LS;Lin Z;Saha TT;Wang C;Jiang H;Zou Z
通讯作者:
Zou Z
DOI:
10.1074/jbc.m114.599597
发表时间:
2014-11
期刊:
The Journal of Biological Chemistry
影响因子:
--
作者:
Jie Zhang;A. Lu;Lulu Kong;Qiaoli Zhang;E. Ling
通讯作者:
Jie Zhang;A. Lu;Lulu Kong;Qiaoli Zhang;E. Ling
DOI:
10.1073/pnas.1222351110
发表时间:
2013-06-04
影响因子:
11.1
作者:
Mortimer, Nathan T.;Goecks, Jeremy;Schlenke, Todd A.
通讯作者:
Schlenke, Todd A.