Encapsulins: Structure, Properties, and Biotechnological Applications.
Encapsulins: Structure, Properties, and Biotechnological Applications.
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DOI：
10.1134/s0006297923010042
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发表时间：
2023-01
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
In 1994 a new class of prokaryotic compartments was discovered, collectively called “encapsulins” or “nanocompartments”. Encapsulin shell protomer proteins self-assemble to form icosahedral structures of various diameters (24-42 nm). Inside of nanocompartments shells, one or several cargo proteins, diverse in their functions, can be encapsulated. In addition, non-native cargo proteins can be loaded into nanocompartments, and shell surfaces can be modified via various compounds, which makes it possible to create targeted drug delivery systems, labels for optical and MRI imaging, and to use encapsulins as bioreactors. This review describes a number of strategies of encapsulins application in various fields of science, including biomedicine and nanobiotechnologies.
影响因子：
5.4
作者：
Efremova MV;Bodea SV;Sigmund F;Semkina A;Westmeyer GG;Abakumov MA
通讯作者：
Abakumov MA
影响因子：
2.8
作者：
Kirykowicz AM;Woodward JD
通讯作者：
Woodward JD