Challenges and opportunities of advanced gliomodulation technologies for excitation-inhibition balance of brain networks.

Challenges and opportunities of advanced gliomodulation technologies for excitation-inhibition balance of brain networks.
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DOI:
10.1016/j.copbio.2021.10.008
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发表时间:
2021-12
影响因子:
7.7
通讯作者:
Kozai TD
Kozai TD
中科院分区:
工程技术1区
文献类型:
--
作者:
Chen K;Stieger KC;Kozai TD

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Recent neuroscience studies have highlighted the critical role of glial cells in information processing. This has increased the demand for technologies that selectively modulate glial cells that regulate the excitation-inhibition balance of neural network function. Engineered technologies that modulate glial activity may be necessary for precise tuning of neural network activity in higher-order brain function. This perspective summarizes how glial cells regulate excitation and inhibition of neural circuits, highlights available technologies for glial modulation, and discusses current challenges and potential opportunities for glial engineering technologies.
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