The role of microRNAs in human liver cancers.
The role of microRNAs in human liver cancers.
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DOI:
10.1053/j.seminoncol.2011.08.001
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发表时间:
2011-12
影响因子:
4
通讯作者:
Patel T
中科院分区:
文献类型:
--
作者:
Braconi C;Henry JC;Kogure T;Schmittgen T;Patel T
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver of global importance. Recent studies of the expression and role of microRNA (miRNA) in HCC are providing new insights into disease pathogenesis. In addition, therapeutic efforts targeting specific miRNAs are being evaluated in animal models of HCC. The potential of miRNAs as biomarkers of disease or prognostic markers is being explored. Herein, we review studies of miRNA expression in human HCC, and discuss recent advances in knowledge about the involvement and role of selected miRNAs in disease pathogenesis, as biomarkers, or as therapeutic targets for HCC.
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影响因子:
6.4
作者:
Huang, Shenglin;He, Xianghuo;Gu, Jianren
通讯作者:
Gu, Jianren
影响因子:
11.2
作者:
Gramantieri, Laura;Ferracin, Manuela;Negrini, Massimo
通讯作者:
Negrini, Massimo
影响因子:
29.4
作者:
Bugianesi, E;Leone, N;Rizzetto, M
通讯作者:
Rizzetto, M
影响因子:
50.3
作者:
Garofalo M;Di Leva G;Romano G;Nuovo G;Suh SS;Ngankeu A;Taccioli C;Pichiorri F;Alder H;Secchiero P;Gasparini P;Gonelli A;Costinean S;Acunzo M;Condorelli G;Croce CM
通讯作者:
Croce CM
DOI:
10.1056/nejmoa0901282
发表时间:
2009-10-08
期刊:
The New England journal of medicine
影响因子:
--
作者:
Ji J;Shi J;Budhu A;Yu Z;Forgues M;Roessler S;Ambs S;Chen Y;Meltzer PS;Croce CM;Qin LX;Man K;Lo CM;Lee J;Ng IO;Fan J;Tang ZY;Sun HC;Wang XW
通讯作者:
Wang XW