Androgens increase lws opsin expression and red sensitivity in male three-spined sticklebacks.
Androgens increase lws opsin expression and red sensitivity in male three-spined sticklebacks.
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DOI：
10.1371/journal.pone.0100330
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Borg B
中科院分区：
文献类型：
--
作者：
Shao YT;Wang FY;Fu WC;Yan HY;Anraku K;Chen IS;Borg B
视觉运动的研究表明，三棘鱼（Gasterosteus aculeatus）在夏季比冬季对红色更敏感，这可能与需要检测雄性的红色繁殖颜色有关。这项研究旨在确定这种红光敏感性的变化是否与生殖生理学有关。在视网膜的性成熟和未成熟的鱼，以及在假手术的男性，去势对照男性，或去势男性植入雄激素11-酮雄烯二酮（11 KA），维持在刺激（L16：D8）或抑制（L 8：D16）光周期的视蛋白基因的mRNA水平进行了检查。在两种性别，红色敏感的视蛋白基因（lws）的mRNA水平较高，在性成熟的鱼比未成熟的。在L16：D8，lws mRNA水平高于完整的去势雄性，并上调11 KA治疗去势雄性。此外，视网膜电图数据证实，性成熟导致较高的相对红色光谱敏感性。L16：D8下的成熟雄性比L 8：D16下的雄性对红光更敏感。L16：D8下的红光敏感性被去势降低，但被11 KA处理增加。因此，在性成熟的雄性棘鱼中，雄激素是通过调节视蛋白基因表达来增强对红光敏感性的关键因素。这是第一个证明性激素可以调节光谱视觉敏感度的研究。
Optomotor studies have shown that three-spined sticklebacks (Gasterosteus aculeatus) are more sensitive to red during summer than winter, which may be related to the need to detect the red breeding colour of males. This study aimed to determine whether this change of red light sensitivity is specifically related to reproductive physiology. The mRNA levels of opsin genes were examined in the retinae of sexually mature and immature fish, as well as in sham-operated males, castrated control males, or castrated males implanted with androgen 11-ketoandrostenedione (11 KA), maintained under stimulatory (L16:D8) or inhibitory (L8:D16) photoperiods. In both sexes, red-sensitive opsin gene (lws) mRNA levels were higher in sexually mature than in immature fish. Under L16:D8, lws mRNA levels were higher in intact than in castrated males, and were up-regulated by 11 KA treatment in castrated males. Moreover, electroretinogram data confirmed that sexual maturation resulted in higher relative red spectral sensitivity. Mature males under L16:D8 were more sensitive to red light than males under L8:D16. Red light sensitivity under L16:D8 was diminished by castration, but increased by 11 KA treatment. Thus, in sexually mature male sticklebacks, androgen is a key factor in enhancing sensitivity to red light via regulation of opsin gene expression. This is the first study to demonstrate that sex hormones can regulate spectral vision sensitivity.
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DOI：
10.1098/rstb.1993.0060
发表时间：
1993-05-29
影响因子：
6.3
作者：
ENDLER, JA
通讯作者：
ENDLER, JA
影响因子：
3.3
作者：
Alekseyenko, O. V.;Baum, M. J.;Cherry, J. A.
通讯作者：
Cherry, J. A.
影响因子：
2.5
作者：
Harbott, Lene K.;Burmeister, Sabrina S.;Fernald, Russell D.
通讯作者：
Fernald, Russell D.
影响因子：
2.8
作者：
Flamarique, Inigo Novales;Cheng, Christiana L.;Reimchen, Thomas E.
通讯作者：
Reimchen, Thomas E.
影响因子：
2.4
作者：
Engstrom-Ost, Jonna;Candolin, Ulrika
通讯作者：
Candolin, Ulrika