Coagulation Factor XIII in Plasma of Patients with Benign and Malignant Gynaecological Tumours
Coagulation Factor XIII in Plasma of Patients with Benign and Malignant Gynaecological Tumours
复制标题
妇科良恶性肿瘤患者血浆凝血因子XIII的研究
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
J. Ubachs
中科院分区：
文献类型：
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作者：
J. W. Wersch;C. Peters;J. Ubachs
对64例新近发现的妇科肿瘤患者进行了纤维蛋白原和凝血因子XIII检测。在这些肿瘤中，26个是良性的，32个是恶性的：最后一组中，有9名患者有转移。没有患者表现出出血或血栓形成的临床迹象。参照组由31名年龄匹配的健康女性组成。对于纤维蛋白原，患者组和对照组之间没有发现明显的差异。良性肿瘤组凝血因子XIII的中位数高于对照组。在妇科肿瘤和转移的患者中，XIII因子显著低于非转移性恶性肿瘤组或良性肿瘤组。
Fibrinogen and factor XIII were measured in sixty-four women with recently detected gynaecological tumours. Twenty-six of these tumours were benign and 32 were malignant: of the last group, nine patients had metastases. No patient showed clinical signs of bleeding or thrombosis. A reference group consisted of 31 age-matched healthy women. For fibrinogen, no significant deviation between the patient groups and the control group was found. The median values of factor XIII were higher in the benign tumour group than in the control group. In patients with a gynaecological tumour and metastases, factor XIII was significantly lower than in the non-metastasized malignancy group or in the benign tumour group.
影响因子：
3.5
作者：
Wojtukiewicz,MZ;Zacharski,LR;Memoli,VA;Kisiel,W;Kudryk,BJ;Rousseau,SM;Stump,DC
通讯作者：
Stump,DC