Electrophoretic collision of a DNA molecule with an insulating post.
Electrophoretic collision of a DNA molecule with an insulating post.
复制标题
DNA 分子与绝缘柱的电泳碰撞。
DOI:
10.1103/physrevlett.93.058102
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发表时间:
2004
影响因子:
8.6
通讯作者:
P. Doyle
中科院分区:
文献类型:
--
作者:
G. Randall;P. Doyle
We study the dynamics of single DNA molecules driven by an electric field into a stationary obstacle. These collisions are broadly classified as "hook" and "roll-off" events. We show that obstacle-induced electric field gradients stretch impacting DNA and thus greatly influence the hooking probability. Consequently, in addition to collision geometry, determination of the hooking probability depends on the Deborah number (De) for 0.5<De<40. Individual DNA impact dynamics are highly configuration sensitive, characteristic of polymers in elongational flows and fields.
影响因子:
56.9
作者:
Perkins, TT;Smith, DE;Chu, S
通讯作者:
Chu, S
影响因子:
8.6
作者:
Huang, LR;Silberzan, P;Craighead, H
通讯作者:
Craighead, H
影响因子:
3.4
作者:
Chou, CF;Tegenfeldt, JO;Austin, RH
通讯作者:
Austin, RH