Long-term results of type B aortic dissection patients with tumor after endovascular repair or optimal medical therapy: a single-center and retrospective cohort study.
Long-term results of type B aortic dissection patients with tumor after endovascular repair or optimal medical therapy: a single-center and retrospective cohort study.
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B型主动脉夹层肿瘤患者血管内修复或最佳药物治疗后的长期结果：单中心回顾性队列研究
DOI：
10.1186/s12893-021-01327-8
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发表时间：
2021-08-18
期刊：
影响因子：
1.9
通讯作者：
Zhou J
中科院分区：
文献类型：
--
作者：
Liang T;Zhu H;Zhang L;Li S;He X;Zhao K;Jing Z;Zhou J
胸主动脉腔内修复术(TEVAR)治疗急性B型主动脉病变的疗效已得到证实，但恶性疾病患者并发急性B型主动脉夹层(ATBAD)时，TEVAR的干预效果尚不清楚。ATBAD患者是从2009年至2019年的电子医疗记录中识别出来的。分析比较两组患者的5年总生存率和无主动脉病变生存率。在40名登记的患者中，27名(67.5%)接受了TEVAR，13名(32.5%)接受了OMT。两组患者的基线特征无显著差异。Kaplan-Meier生存曲线显示，TEVAR组的5年总生存率和5年无主动脉病变生存率均好于OMT组。未调整风险的Cox比例风险模型显示，与OMT组相比，TEVAR组的5年总死亡率(HR，0.17；95%CI，0.05-0.56)降低了83.0%，主动脉疾病相关风险(HR，0.08；95%CI，0.02-0.39)更低。在调整了年龄、性别、吸烟、饮酒和合并疾病(糖尿病、高血压和冠状动脉疾病)后，与OMT组相比，TEVAR组5年总死亡率的风险比降低了78.0%(HR，0.22；95%CI，0.06.0.81)，主动脉疾病相关死亡的风险降低了93.0%(HR，0.07；95%CI，0.01-0.61)。在按年龄、性别分层的队列中，与OMT组相比，TEVAR组5年内总体或与主动脉疾病相关的死亡风险相对较低。与OMT相比，TEVAR提高了患有单一类型恶性肿瘤的ATBAD患者队列中的5年总体存活率和无主动脉疾病存活率。
The effect of thoracic endovascular aortic repair (TEVAR) for acute Type B aortic has been confirmed, However, when patients with malignant disease suffer from acute type B aortic dissection (ATBAD), the effect of TEVAR intervention is still unclear. ATBAD patients were identified from electronic medical records between 2009 and 2019. The 5 year overall and aortic-disease free survival rates were analyzed and compared between the two groups. Of the 40 enrolled patients, 27 (67.5%) received TEVAR and 13 (32.5%) received OMT. The baseline characteristics of the two groups were not significantly different. Kaplan‒Meier survival curve showed that the 5 year overall survival and 5 year aortic-disease free survival of the TEVAR group were better than those of the OMT group. The Cox proportional hazard model with unadjusted risk showed an 83.0% decrease in 5 year overall mortality (HR, 0.17; 95% CI, 0.05–0.56) and a lower aortic-disease related risk (HR, 0.08; 95% CI, 0.02–0.39) in TEVAR group compared to OMT group. After adjusted for age, gender, smoking, drinking and comorbidities (diabetes mellitus, hypertension and coronary artery diseases), the hazard ratio of 5 year overall mortality was 78.0% lower (HR, 0.22; 95% CI, 0.06.0.81) and the risk of aortic-disease related mortality was 93.0% lower (HR, 0.07; 95% CI, 0.01–0.61) in TEVAR group compared to OMT group. In the cohort stratified by age, sex, the risk of the 5 year overall or aortic-disease related mortality in TEVAR group was relatively reduced compared to OMT group. Compared to OMT, TEVAR improves the 5 year overall and aortic-disease free survival rates in the cohort of ATBAD patients with a single type of malignant tumors.
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影响因子：
1.6
作者：
Hashiyama N;Goda M;Uchida K;Isomatsu Y;Suzuki S;Mo M;Nishida T;Masuda M
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影响因子：
168.9
作者：
Nienaber, Christoph A.;Clough, Rachel E.
通讯作者：
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DOI：
10.1016/j.jtcvs.2019.11.127
发表时间：
2021-06-12
影响因子：
6
作者：
Xiang, Dongqiao;Kan, Xuefeng;Zheng, Chuansheng
通讯作者：
Zheng, Chuansheng